| Mystery Case Files: Huntsville | November 14, 2005 | Big Fish Games |
| Mystery Case Files: Prime Suspects | April 6, 2006 | Big Fish Games |
| Mystery Case Files: Ravenhearst | December 15, 2006 | Big Fish Games |
| Mystery Case Files: Madame Fate | November 7, 2007 | Big Fish Games |
| Mystery Case Files: Agent X | April 15, 2008 | — |
| Mystery Case Files: MillionHeir | September 8, 2008 | Big Fish Games |
| Mystery Case Files: Return to Ravenhearst | November 26, 2008 | Big Fish Games |
| Mystery Case Files: Dire Grove | November 25, 2009 | Big Fish Games |
| Mystery Case Files: The Malgrave Incident | June 27, 2011 | Big Fish Games |
| Mystery Case Files: Escape From Ravenhearst | November 24, 2011 | Big Fish Games |
| Mystery Case Files: Shadow Lake | December 26, 2012 | Big Fish Games |
| Mystery Case Files: Spirits of Blackpool | October 24, 2013 | — |
| Mystery Case Files: Fate's Carnival | November 26, 2013 | Elephant Games |
| Mystery Case Files: Dire Grove, Sacred Grove | November 26, 2014 | Elephant Games |
| Mystery Case Files: Key to Ravenhearst | October 27, 2015 | Eipix Entertainment |
| Mystery Case Files: Ravenhearst Unlocked | November 27, 2015 | Eipix Entertainment |
| Mystery Case Files: 13th Skull | August 18, 2016 | Big Fish Games |
| Mystery Case Files: Broken Hour | November 22, 2016 | Eipix Entertainment |
| Mystery Case Files: The Black Veil | March 23, 2017 | Eipix Entertainment |
| Mystery Case Files: The Revenant's Hunt | November 20, 2017 | Eipix Entertainment |
| Mystery Case Files: Rewind | June 21, 2018 | Eipix Entertainment |
| Mystery Case Files: The Countess | November 23, 2018 | Eipix Entertainment |
| Mystery Case Files: Moths to a Flame | September 21, 2019 | Eipix Entertainment |
| Mystery Case Files: Black Crown | November 28, 2019 | Eipix Entertainment |
| Mystery Case Files: The Harbinger | August 20, 2020 | GrandMA Studios |
| Mystery Case Files: Crossfade | November 25, 2020 | GrandMA Studios |
| Mystery Case Files: Incident at Pendle Tower | November 23, 2021 | GrandMA Studios |
| Mystery Case Files: The Last Resort | November 22, 2022 | GrandMA Studios |
| Mystery Case Files: The Dalimar Legacy | March 16, 2023 | GrandMA Studios |
| Mystery Case Files: A Crime in Reflection | November 21, 2023 | GrandMA Studios |
| Mystery Case Files: The Riddle of Mrs. Bishop | November 26, 2024 | GrandMA Studios |
| Mystery Case Files: House That Love Built | November 26, 2025 | GrandMA Studios |