- 12 orbitsReleased: 2016Platforms: Microsoft Windows, macOS, Linux
- GunslugsReleased: 2016Developer: Orange Pixel
- I Expect You to DieReleased: 2016Developer: Schell Games
- Jet Set KnightsReleased: 2016Developer: FobTi interactive
- Super Intergalactic GangReleased: January 4, 2016Platforms: Microsoft Windows
- Beyond RealityReleased: January 8, 2016Publisher: Aldorlea Games
- Big Action Mega Fight!Released: January 12, 2016Developer: Double Stallion
- Dragon's Dogma: Dark ArisenReleased: January 15, 2016Developer: Capcom
- OpenClonkReleased: January 16, 2016Series: Clonk
- CrashlandsReleased: January 21, 2016Developer: Butterscotch Shenanigans
- DinocideReleased: January 21, 2016Developer: AtomicTorch Studio
- The MinotaurReleased: January 21, 2016Developer: Ratalaika Games
- Super Phantom CatReleased: January 25, 2016Platforms: Microsoft Windows, Android
- ToroReleased: January 26, 2016Developer: Recotechnology S.L.
- FullBlastReleased: January 28, 2016Platforms: Microsoft Windows, macOS, Wii U
- Blitz BreakerReleased: February 2, 2016Platforms: Microsoft Windows
- FortifiedReleased: February 3, 2016Engine: Unreal Engine 4
- The Chosen RPGReleased: February 4, 2016Platforms: Microsoft Windows
- DefragmentedReleased: February 12, 2016Platforms: Microsoft Windows, macOS, Linux
- Control Craft 2Released: February 15, 2016Platforms: Microsoft Windows, macOS
- ZHEROSReleased: February 15, 2016Platforms: Microsoft Windows
- Attack on TitanReleased: February 18, 2016Developer: Omega Force
- The SwordsReleased: February 18, 2016Developer: Sunhead Games
- Zeus vs Monsters - Math Game for kidsReleased: February 18, 2016Developer: Peaksel
- Karaski: What Goes Up...Released: March 2, 2016Platforms: Microsoft Windows
- Chicken Invaders 2Released: March 4, 2016Developer: InterAction studios
- Banzai EscapeReleased: March 16, 2016Platforms: Microsoft Windows
- Prison Run and GunReleased: March 16, 2016Platforms: Microsoft Windows, macOS, Linux
- The PerfectionistReleased: March 18, 2016Engine: RPG Maker VX Ace
- Wish ProjectReleased: March 22, 2016Engine: Microsoft XNA
- Thorne - Death MerchantsReleased: March 25, 2016Publisher: Aldorlea Games
- Angry Video Game Nerd II: ASSimilationReleased: March 29, 2016Developer: FreakZone Games
- Leap of FateReleased: March 30, 2016Developer: Clever Plays
- Stikbold! A Dodgeball AdventureReleased: April 2016Publisher: Curve Games
- Good RobotReleased: April 5, 2016Platforms: Microsoft Windows
- GlitchrunnersReleased: April 8, 2016Publisher: Green Man Gaming Publishing
- StarsOneReleased: April 8, 2016Platforms: Microsoft Windows, macOS, Linux
- Gravity DenReleased: April 15, 2016Publisher: Volens Nolens Games
- Strike Force: Desert ThunderReleased: April 25, 2016Platforms: Microsoft Windows
- Kirby: Planet RobobotReleased: April 28, 2016Developer: HAL Laboratory
- Flesh EatersReleased: May 3, 2016Engine: GameMaker
- MOP Operation CleanupReleased: May 3, 2016Developer: EnsenaSoft
- Omega AgentReleased: May 4, 2016Developer: Fireproof Studios
- EcotoneReleased: May 6, 2016Developer: Sundae Factory
- Gunmetal Arcadia ZeroReleased: May 6, 2016Developer: Minor Key Games
- GoliathReleased: May 12, 2016Developer: Whalebox Studio
- InsincereReleased: May 12, 2016Developer: Astronomic Games
- MurasakiReleased: May 12, 2016Publisher: Playism
- Sins Of The Demon RPGReleased: May 13, 2016Platforms: Microsoft Windows
- ArkshotReleased: May 19, 2016Publisher: Digerati
- Just a ClericReleased: May 19, 2016Engine: Multimedia Fusion
- Where's My Helmet?Released: May 20, 2016Publisher: My Way Games
- Teenage Mutant Ninja Turtles: Mutants in ManhattanReleased: May 24, 2016Platforms: PlayStation 3, Microsoft Windows
- Miko MoleReleased: May 25, 2016Developer: EnsenaSoft
- BARRIER XReleased: May 27, 2016Publisher: HypeTrain Digital
- Vairon's WrathReleased: May 27, 2016Platforms: Microsoft Windows
- Dead Island: Definitive CollectionReleased: May 31, 2016Platforms: Microsoft Windows, Linux
- Senran Kagura Shinovi VersusReleased: June 1, 2016Developer: Tamsoft
- Zaccaria PinballReleased: June 16, 2016Platforms: Microsoft Windows, macOS, Linux, Android, Xbox Series X and Series S
- Storm Of Spears RPGReleased: June 17, 2016Developer: Warfare Studios
- BoidReleased: July 8, 2016Platforms: Microsoft Windows
- Lion QuestReleased: July 11, 2016Platforms: Microsoft Windows, macOS, Linux
- Rot GutReleased: July 12, 2016Engine: Flixel
- Crush Your EnemiesReleased: July 13, 2016Developer: Vile Monarch
- 10 Second Ninja XReleased: July 19, 2016Developer: Four Circle Interactive
- Red Rope: Don't Fall BehindReleased: July 21, 2016Platforms: Microsoft Windows, macOS, Linux
- Lovely Planet ArcadeReleased: July 22, 2016Platforms: Microsoft Windows, macOS, Linux
- Sky to Fly: Soulless LeviathanReleased: July 22, 2016Developer: AIVIK LLC
- NaryReleased: August 2, 2016Developer: Khud0
- Mibibli's QuestReleased: August 4, 2016Developer: Resnijars
- Frozen StateReleased: August 5, 2016Platforms: Microsoft Windows, macOS, Linux
- Random Access MurderReleased: August 5, 2016Platforms: Microsoft Windows, macOS, Linux
- Sneak ThiefReleased: August 6, 2016Developer: NickRizzoGames
- Infectonator: SurvivorsReleased: August 8, 2016Developer: Toge Productions
- #KILLALLZOMBIESReleased: August 10, 2016Developer: Beatshapers
- WandsReleased: August 18, 2016Platforms: Microsoft Windows, Android
- Crawlers and BrawlersReleased: August 22, 2016Engine: Microsoft XNA
- ZombasiteReleased: August 23, 2016Platforms: Microsoft Windows, macOS, Linux
- Mount WingsuitReleased: August 25, 2016Platforms: Microsoft Windows
- The Other 99Released: August 25, 2016Platforms: Microsoft Windows
- The Storm Guard: Darkness is ComingReleased: August 25, 2016Developer: Bitmen Studios
- BeeftacularReleased: August 26, 2016Developer: Retrific
- Thorne - Son of Slaves (Ep.2)Released: August 26, 2016Publisher: Aldorlea Games
- The Last HopeReleased: August 29, 2016Platforms: Microsoft Windows
- Minds EyesReleased: August 31, 2016Platforms: Microsoft Windows
- Intensive ExposureReleased: September 6, 2016Developer: Fireline Games
- Flat HeroesReleased: September 8, 2016Developer: Parallel Circles
- NightmareZReleased: September 8, 2016Developer: Anamik Majumdar
- Iron Sea DefendersReleased: September 9, 2016Developer: Creobit
- Strike Force: Arctic StormReleased: September 21, 2016Platforms: Microsoft Windows
- Dungeons & DarknessReleased: September 29, 2016Publisher: Playism
- Zombo Buster RisingReleased: October 3, 2016Developer: Firebeast
- Laser Disco DefendersReleased: October 6, 2016Publisher: Excalibur Publishing
- 20XXReleased: October 12, 2016Platforms: Microsoft Windows
- WarshiftReleased: October 12, 2016Platforms: Microsoft Windows
- Draw SlasherReleased: October 13, 2016Platforms: Microsoft Windows, macOS, Linux
- 9th Dawn IIReleased: October 17, 2016Developer: Valorware
- Zombie Birds First Encounter HalloweenReleased: October 19, 2016Developer: Magnussoft
- Crown Champion: Legends of the ArenaReleased: October 21, 2016Developer: Pilgrim Adventures
- Bubble BlowoutReleased: October 24, 2016Developer: EnsenaSoft