- Typing Fingers - EnemyReleased: January 24, 2021Platforms: Microsoft Windows, macOS
- Dead Cells: Fatal FallsReleased: January 26, 2021Developer: Evil Empire, Motion Twin
- Farm Frenzy: RefreshedReleased: January 27, 2021Developer: GameOn Production
- A Painter's Tale: Curon, 1950Released: January 28, 2021Platforms: Microsoft Windows, macOS
- DevourReleased: January 28, 2021Platforms: Microsoft Windows, macOS
- Fate of the Storm GodsReleased: January 28, 2021Developer: Choice of Games
- Garbage: Hobo ProphecyReleased: January 28, 2021Publisher: GrabTheGames
- Miska's CaveReleased: January 28, 2021Platforms: Microsoft Windows, macOS, Linux
- SarawakReleased: January 28, 2021Platforms: Microsoft Windows, macOS, Linux
- Lost CavesReleased: January 29, 2021Platforms: Microsoft Windows, macOS
- Melancholy LoveReleased: January 29, 2021Publisher: Kikai Digital
- Populus RunReleased: January 29, 2021Developer: Fiftytwo
- Red Hands – 2-Player GameReleased: January 29, 2021Developer: Peaksel
- Post CardsReleased: January 30, 2021Developer: Sokpop Collective
- The Captain is DeadReleased: January 31, 2021Platforms: Microsoft Windows, macOS
- URGReleased: February 2021Platforms: Microsoft Windows, macOS, Linux
- Ero TennisReleased: February 2, 2021Platforms: Microsoft Windows, macOS, Linux
- ValheimReleased: February 2, 2021Developer: Iron Gate Studio
- War on the SeaReleased: February 2, 2021Developer: Killerfish Games
- Cyber ManhuntReleased: February 3, 2021Platforms: Microsoft Windows, macOS
- PsycholonialsReleased: February 3, 2021Developer: Andrew Hussie
- Spooksville, USAReleased: February 3, 2021Developer: Axol Studio, LLC
- A Hole In SpaceReleased: February 4, 2021Platforms: Microsoft Windows, macOS
- Cat's MenaceReleased: February 4, 2021Engine: Godot
- Chess Brain: Dark TroopsReleased: February 4, 2021Publisher: QUByte Interactive
- Haunted NightmaresReleased: February 4, 2021Platforms: Microsoft Windows, macOS
- QompReleased: February 4, 2021Developer: Stuffed Wombat
- Comet 64Released: February 5, 2021Platforms: Microsoft Windows, macOS, Linux
- Instant Farmer - Logic PuzzleReleased: February 5, 2021Developer: Mens Sana Interactive
- Lumen.Released: February 5, 2021Developer: Lykke Studios
- The Great Plague ExodusReleased: February 5, 2021Platforms: Microsoft Windows, macOS, Linux
- RevertiaReleased: February 7, 2021Publisher: PLiCy
- Space KettleReleased: February 7, 2021Platforms: Microsoft Windows, macOS
- SpaceNETReleased: February 7, 2021Platforms: Microsoft Windows, macOS, Linux
- HuniePop 2: Double DateReleased: February 8, 2021Developer: HuniePotDev
- DetoursReleased: February 10, 2021Platforms: Microsoft Windows, macOS, Linux
- AquadineReleased: February 11, 2021Developer: SoftColors
- Bow & Crystal Tower DefenseReleased: February 11, 2021Platforms: Microsoft Windows, macOS, Linux
- Mini CountriesReleased: February 12, 2021Platforms: Microsoft Windows, macOS, Linux
- BrawlerReleased: February 14, 2021Engine: Multimedia Fusion
- Half Past Fate: Romantic DistancingReleased: February 14, 2021Publisher: Way Down Deep
- Celestial HeartsReleased: February 15, 2021Engine: RPG Maker MZ
- Bravery Network OnlineReleased: February 16, 2021Platforms: Microsoft Windows, macOS
- Pathfinders: MemoriesReleased: February 16, 2021Developer: Mens Sana Interactive
- Purrfect Apawcalypse: Love at Furst BiteReleased: February 16, 2021Platforms: Microsoft Windows, macOS, Linux
- Learning FactoryReleased: February 18, 2021Developer: Luden.io
- MutropolisReleased: February 18, 2021Publisher: Application Systems Heidelberg
- RoboBunnies In Space!Released: February 18, 2021Platforms: Microsoft Windows, macOS
- Woodle DeluxeReleased: February 18, 2021Developer: Chubby Pixel
- Kosmonavtes: Escape RealityReleased: February 19, 2021Platforms: Microsoft Windows, macOS, Linux
- Pawn of the DeadReleased: February 19, 2021Platforms: Microsoft Windows, macOS, Linux
- Quick RaceReleased: February 19, 2021Platforms: Microsoft Windows, macOS, Linux
- Survival VacancyReleased: February 19, 2021Platforms: Microsoft Windows, macOS, Linux
- Survival ZReleased: February 19, 2021Developer: Ember Entertainment
- Super Raft BoatReleased: February 21, 2021Platforms: Microsoft Windows, macOS
- Incremental Epic HeroReleased: February 22, 2021Platforms: Microsoft Windows, macOS
- Kosmonavtes: Academy EscapeReleased: February 22, 2021Platforms: Microsoft Windows, macOS, Linux
- A Western DramaReleased: February 23, 2021Developer: TriBit Studio
- Black BabyReleased: February 23, 2021Platforms: Microsoft Windows, macOS, Linux
- Collapse: A Political SimulatorReleased: February 23, 2021Developer: Kremlingames
- Of Mice and MoggiesReleased: February 23, 2021Developer: Bippinbits
- Relaxing KiteReleased: February 23, 2021Platforms: Microsoft Windows, macOS, Linux
- Geneforge 1 - MutagenReleased: February 24, 2021Developer: Spiderweb Software
- Kitty TacticsReleased: February 24, 2021Platforms: Microsoft Windows, macOS, Linux
- Room to GrowReleased: February 25, 2021Platforms: Microsoft Windows, macOS
- Tiny Room Stories: Town MysteryReleased: February 25, 2021Platforms: Microsoft Windows, macOS
- Tiny TrafficReleased: February 25, 2021Platforms: Microsoft Windows, macOS
- Baobabs Mausoleum Grindhouse Edition - Country of Woods and Creepy TalesReleased: February 26, 2021Platforms: Microsoft Windows, macOS
- Flowers Blooming at the End of SummerReleased: February 26, 2021Platforms: Microsoft Windows, macOS, Linux
- Hack GridReleased: February 26, 2021Platforms: Microsoft Windows, macOS, Linux
- Hero Among UsReleased: February 26, 2021Platforms: Microsoft Windows, macOS, Linux
- HoaReleased: February 26, 2021Platforms: Microsoft Windows, macOS, Xbox Series X and Series S
- Hot BrassReleased: February 26, 2021Platforms: Microsoft Windows, macOS
- Pavlov's HouseReleased: February 26, 2021Platforms: Microsoft Windows, macOS
- Rhythm DoctorReleased: February 26, 2021Developer: 7th Beat Games
- WILD-9Released: February 26, 2021Developer: Sokpop Collective
- Urtuk: The DesolationReleased: February 27, 2021Engine: libGDX
- Hamster All-StarsReleased: February 28, 2021Developer: Sokpop Collective
- Puzlkind Jigsaw PuzzlesReleased: March 2021Platforms: Microsoft Windows, macOS
- Spirit ClashReleased: March 2021Platforms: Microsoft Windows, macOS
- Wheelie King OnlineReleased: March 2021Platforms: Microsoft Windows, macOS, Linux
- Crypto: Against All OddsReleased: March 2, 2021Publisher: PID Games
- Introvert: A Teenager SimulatorReleased: March 2, 2021Developer: Euphoric Brothers
- GravitreX ArcadeReleased: March 3, 2021Platforms: Microsoft Windows, macOS, Linux
- Manic ArchersReleased: March 3, 2021Platforms: Microsoft Windows, macOS, Linux
- Merchants of the CaribbeanReleased: March 3, 2021Developer: GameOn Production
- Loop HeroReleased: March 4, 2021Developer: Four Quarters
- College Kings - The Complete SeasonReleased: March 5, 2021Platforms: Microsoft Windows, macOS, Linux
- Conquer and Breed the Demon QueenReleased: March 5, 2021Publisher: Cherry Kiss Games
- Lion Quest InfinityReleased: March 5, 2021Platforms: Microsoft Windows, macOS, Linux
- MitozaReleased: March 5, 2021Publisher: Second Maze
- Power of TwoReleased: March 5, 2021Platforms: Microsoft Windows, macOS, Linux
- Sp!ngReleased: March 5, 2021Developer: SMG Studio
- I'm on Observation DutyReleased: March 6, 2021Developer: Notovia
- Coloring Book for KidsReleased: March 8, 2021Developer: Peaksel
- Small LifeReleased: March 8, 2021Platforms: Microsoft Windows, macOS
- Blind DriveReleased: March 10, 2021Platforms: Microsoft Windows, macOS
- Rogue GlitchReleased: March 10, 2021Publisher: Numskull Games
- Cyanide & Happiness - Freakpocalypse (Episode 1)Released: March 11, 2021Developer: Skeleton Crew Studios, Explosm
- Daughter of EssenceReleased: March 12, 2021Platforms: Microsoft Windows, macOS