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- Final Fantasy I & II: Dawn of SoulsReleased: 2004Developer: Tose Co.
- Phoenix Wright: Ace Attorney – Trials and TribulationsReleased: January 23, 2004Developer: Capcom
- Metroid: Zero MissionReleased: February 9, 2004Developer: Nintendo Research & Development 1
- Kirby & the Amazing MirrorReleased: April 15, 2004Developer: Flagship
- Mario Golf: Advance TourReleased: April 22, 2004Developer: Camelot Software Planning
- Mega Man Zero 3Released: April 23, 2004Developer: Inti Creates
- Sonic Advance 3Released: June 7, 2004Developer: Sonic Team, Dimps
- Rockman EXE 4.5 Real OperationReleased: August 6, 2004Developer: Capcom
- Mario Pinball LandReleased: August 26, 2004Developer: Silverball Studios
- F-Zero ClimaxReleased: October 21, 2004Developer: Suzak Inc.
- The Legend of Zelda: The Minish CapReleased: November 4, 2004Developer: Capcom
- Mario Party AdvanceReleased: January 13, 2005Developer: Hudson Soft
- Yoshi Touch & GoReleased: January 27, 2005Developer: Nintendo Entertainment Analysis & Development
- DK: King of SwingReleased: February 4, 2005Developer: Paon DP
- Kirby: Canvas CurseReleased: March 24, 2005Developer: HAL Laboratory
- Mega Man Zero 4Released: April 21, 2005Developer: Inti Creates
- Brain Age: Train Your Brain in Minutes a Day!Released: May 19, 2005Developer: Nintendo Software Planning & Development
- Fire Emblem: The Sacred StonesReleased: May 23, 2005Developer: Intelligent Systems
- Big Brain AcademyReleased: June 30, 2005Developer: Nintendo Entertainment Analysis & Development
- Advance Wars: Dual StrikeReleased: August 22, 2005Developer: Intelligent Systems
- Mario Tennis: Power TourReleased: September 13, 2005Developer: Camelot Software Planning
- Mario Kart DSReleased: November 14, 2005Developer: Nintendo Entertainment Analysis & Development
- YakuzaReleased: December 8, 2005Series: Yakuza
- Animal Crossing: Wild WorldReleased: March 31, 2006Developer: Nintendo Entertainment Analysis & Development
- Mother 3Released: April 20, 2006Developer: HAL Laboratory
- Metroid Prime HuntersReleased: May 23, 2006Developer: Nintendo Software Technology
- Star Fox CommandReleased: August 3, 2006Developer: Q-Games, Nintendo Entertainment Analysis & Development
- Mario vs. Donkey Kong 2: March of the MinisReleased: September 25, 2006Developer: Nintendo Software Technology
- Kirby: Squeak SquadReleased: November 2, 2006Developer: Flagship
- Yoshi's Island DSReleased: November 13, 2006Developer: Artoon
- The Legend of Zelda: Twilight PrincessReleased: December 2, 2006Developer: Nintendo Entertainment Analysis & Development
- WarioWare: Smooth MovesReleased: December 2, 2006Developer: Intelligent Systems, Nintendo Software Planning & Development
- Pokémon RangerReleased: December 7, 2006Developer: HAL Laboratory
- Yakuza 2Released: December 7, 2006Series: Yakuza
- Wario: Master of DisguiseReleased: January 18, 2007Developer: Suzak Inc.
- Star Fox 64Released: April 17, 2007Developer: Nintendo Entertainment Analysis & Development
- The Legend of Zelda: Phantom HourglassReleased: June 23, 2007Developer: Nintendo Entertainment Analysis & Development
- DK Jungle ClimberReleased: August 9, 2007Developer: Paon DP
- Brunswick Pro BowlingReleased: August 28, 2007Developer: Point of View, Inc.
- Super Paper MarioReleased: September 20, 2007Developer: Intelligent Systems
- Super Mario GalaxyReleased: November 2007Developer: Nintendo Entertainment Analysis & Development
- Mario Party DSReleased: November 8, 2007Developer: Hudson Soft
- Rayman Raving Rabbids 2Released: November 15, 2007Engine: Jade
- PixelJunk MonstersReleased: December 6, 2007Developer: Q-Games
- 1080° SnowboardingReleased: January 15, 2008Developer: Nintendo Entertainment Analysis & Development
- Pokémon Ranger: Shadows of AlmiaReleased: March 20, 2008Developer: Creatures
- Super Mario RPGReleased: June 24, 2008Developer: Square
- Paper PlaneReleased: December 24, 2008Developer: Intelligent Systems, Nintendo Software Planning & Development, Nintendo Research & Development 1
- Clu Clu LandReleased: March 6, 2009Developer: Nintendo Research & Development 1
- Pokémon Mystery Dungeon: Explorers of SkyReleased: April 18, 2009Developer: Chunsoft
- Swords & SoldiersReleased: May 15, 2009Developer: Ronimo Games
- MinecraftReleased: May 17, 2009Developer: Mojang Studios, Microsoft
- Famicom WarsReleased: May 19, 2009Developer: Intelligent Systems
- Mario & Luigi: Bowser's Inside StoryReleased: October 9, 2009Developer: AlphaDream
- Style SavvyReleased: October 23, 2009Developer: Syn Sophia
- BayonettaReleased: October 29, 2009Series: Bayonetta
- Fire Emblem GaidenReleased: November 4, 2009Developer: Intelligent Systems
- The Legend of Zelda: Spirit TracksReleased: December 7, 2009Developer: Nintendo Entertainment Analysis & Development
- Toki ToriReleased: January 29, 2010Developer: Two Tribes
- Picross 3DReleased: March 5, 2010Developer: HAL Laboratory
- Pokémon Ranger: Guardian SignsReleased: March 6, 2010Developer: Creatures
- Super Mario Galaxy 2Released: May 23, 2010Developer: Nintendo Entertainment Analysis & Development
- Xenoblade ChroniclesReleased: June 10, 2010Developer: Monolith Soft Inc.
- Secret Files: TunguskaReleased: June 22, 2010Developer: Animation Arts
- Metroid: Other MReleased: August 31, 2010Developer: D-Rockets, Nintendo Software Planning & Development, Team Ninja
- Sonic ColorsReleased: November 12, 2010Developer: Sonic Team
- Mario vs. Donkey Kong: Mini-Land Mayhem!Released: November 14, 2010Developer: Nintendo Software Technology
- PyoroReleased: June 6, 2011Developer: Intelligent Systems, Nintendo Software Planning & Development, Nintendo Research & Development 1
- Kirby Mass AttackReleased: August 4, 2011Developer: HAL Laboratory
- Deus Ex: Human RevolutionReleased: August 23, 2011Developer: Eidos Montreal
- Tekken Tag Tournament 2Released: September 14, 2011Developer: Bandai Namco Entertainment
- Skylanders: Spyro's AdventureReleased: October 14, 2011Developer: Toys for Bob
- Batman: Arkham CityReleased: October 18, 2011Developer: WB Games Montréal, Rocksteady Studios, Iron Galaxy Studios, Virtuos, Feral Interactive
- Kirby's Return to Dream LandReleased: October 24, 2011Developer: HAL Laboratory
- Shantae: Risky's RevengeReleased: October 27, 2011Developer: WayForward Technologies
- The Legend of Zelda: Skyward SwordReleased: November 18, 2011Developer: Nintendo Entertainment Analysis & Development
- Trine 2Released: December 7, 2011Developer: Frozenbyte
- WarioWare, Inc.: Mega Microgames!Released: December 15, 2011Developer: Nintendo Research & Development 1
- Bridge Constructor PlaygroundReleased: 2012Developer: ClockStone
- Need for Speed: Most WantedReleased: 2012Developer: Criterion Games
- Your Shape: Fitness Evolved 2013Released: 2012Platforms: Wii U
- Resident Evil: RevelationsReleased: January 26, 2012Developer: Capcom, Tose Co.
- Mass Effect 3Released: March 6, 2012Developer: Bioware
- Ninja Gaiden 3Released: March 20, 2012Developer: Team Ninja
- Sniper Elite V2Released: April 30, 2012Developer: Rebellion Developments
- Lego Batman 2: DC Super HeroesReleased: June 19, 2012Developer: Traveller's Tales
- Dragon Quest XReleased: August 2, 2012Developer: Square Enix, Yuji Horii
- Darksiders IIReleased: August 14, 2012Developer: Vigil Games
- Madden NFL 13Released: August 28, 2012Developer: EA Orlando
- FIFA 13Released: September 25, 2012Developer: EA Vancouver
- Bad PiggiesReleased: September 27, 2012Series: Angry Birds
- Just Dance 4Released: October 2, 2012Developer: Ubisoft Milan
- NBA 2K13Released: October 5, 2012Developer: Visual Concepts
- 007 LegendsReleased: October 16, 2012Developer: Eurocom
- Skylanders: GiantsReleased: October 21, 2012Developer: Toys for Bob
- Giana Sisters: Twisted DreamsReleased: October 23, 2012Developer: Black Forest Games
- Assassin's Creed IIIReleased: October 30, 2012Developer: Ubisoft Romania, Ubisoft Annecy, Ubisoft Quebec
- Call of Duty: Black Ops IIReleased: November 12, 2012Developer: Treyarch
- Sonic & All-Stars Racing TransformedReleased: November 16, 2012Developer: Sumo Digital