- Rugrats: Studio TourReleased: November 10, 1999Developer: N-Space
- Earthworm Jim: Menace 2 the GalaxyReleased: November 16, 1999Series: Earthworm Jim
- Donkey Kong 64Released: November 22, 1999Developer: Rare Ltd.
- Castlevania: Legacy of DarknessReleased: November 30, 1999Publisher: Konami
- BugdomReleased: December 1, 1999Developer: Pangea Software
- Bugdom 2Released: December 1, 1999Developer: Pangea Software
- Strider 2Released: December 13, 1999Developer: Capcom
- Hugo: The Quest for the SunstonesReleased: 2000Developer: Interactive Television Entertainment
- Rhino RumbleReleased: 2000Developer: Telegames
- Kirby 64: The Crystal ShardsReleased: March 24, 2000Developer: HAL Laboratory
- Tomba! 2: The Evil Swine ReturnReleased: June 16, 2000Developer: Whoopee Camp
- Spyro: Year of the DragonReleased: October 11, 2000Developer: Insomniac Games
- Tweety's High-Flying AdventureReleased: November 2000Platforms: Game Boy Color
- Banjo-TooieReleased: November 20, 2000Developer: Rare Ltd.
- Bugs Bunny & Taz: Time BustersReleased: November 24, 2000Platforms: Microsoft Windows
- MerlinReleased: December 2000Developer: RFX Interactive
- The Lion King: Simba's Mighty AdventureReleased: December 22, 2000Publisher: Disney Interactive Studios
- Das Geheimnis der Happy Hippo-InselReleased: 2001Developer: Kritzelkratz 3000 GmbH
- Hugo: Black Diamond FeverReleased: 2001Developer: Interactive Television Entertainment
- Croc 2Released: January 23, 2001Developer: Winning Entertainment Group
- Conker's Bad Fur DayReleased: March 5, 2001Developer: Rare Ltd.
- Klonoa 2: Lunatea's VeilReleased: March 22, 2001Developer: Sony Interactive Entertainment
- Pinobee: Wings of AdventureReleased: June 11, 2001Developer: Artoon
- Atlantis: The Lost EmpireReleased: June 14, 2001Platforms: Game Boy Color
- Sonic Adventure 2Released: June 19, 2001Developer: Sonic Team
- The Land Before TimeReleased: July 14, 2001Platforms: Game Boy Color
- Klonoa: Empire of DreamsReleased: July 19, 2001Developer: Namco
- Mega Man Xtreme 2Released: July 19, 2001Developer: Capcom
- Wario Land 4Released: August 21, 2001Developer: Nintendo Research & Development 1
- Atlantis: The Lost EmpireReleased: September 28, 2001Genre: platform game
- Crash Bandicoot: The Wrath of CortexReleased: October 29, 2001Developer: Traveller's Tales
- Oddworld: Munch's OddyseeReleased: November 15, 2001Developer: Oddworld Inhabitants
- Frogger's Adventures: Temple of the FrogReleased: November 30, 2001Developer: Konami
- Jak and Daxter: The Precursor LegacyReleased: December 3, 2001Developer: Naughty Dog
- Woody Woodpecker: Escape from Buzz Buzzard ParkReleased: December 7, 2001Developer: Eko Software
- Sonic AdvanceReleased: December 20, 2001Developer: Sonic Team, Dimps
- Gremlins: Stripe vs. GizmoReleased: 2002Developer: Magic Pockets
- Hugo: The Evil MirrorReleased: 2002Developer: Interactive Television Entertainment
- Sonic Adventure 2: BattleReleased: 2002Developer: Sonic Team
- Pac-Man World 2Released: February 24, 2002Developer: Namco Hometek Inc.
- Crash Bandicoot: The Huge AdventureReleased: February 25, 2002Series: Crash Bandicoot
- Scooby-Doo! Night of 100 FrightsReleased: May 20, 2002Developer: Heavy Iron Studios
- Frogger Advance: The Great QuestReleased: May 28, 2002Developer: Konami
- Ape Escape 2Released: July 18, 2002Developer: Japan Studio
- Klonoa 2: Dream Champ TournamentReleased: August 6, 2002Developer: Namco
- Super Monkey Ball 2Released: August 25, 2002Developer: Amusement Vision
- Densetsu no StafyReleased: September 6, 2002Developer: Tose Co.
- Ty the Tasmanian TigerReleased: September 10, 2002Developer: Krome Studios
- Sly Cooper and the Thievius RaccoonusReleased: September 23, 2002Developer: Sanzaru Games
- Blinx: The Time SweeperReleased: October 7, 2002Developer: Artoon
- ToeJam & Earl III: Mission to EarthReleased: October 23, 2002Developer: ToeJam & Earl Productions
- Spyro: Enter the DragonflyReleased: November 3, 2002Platforms: Nintendo GameCube
- Ratchet & ClankReleased: November 4, 2002Developer: Insomniac Games
- Frogger BeyondReleased: December 6, 2002Developer: Konami
- Sonic Advance 2Released: December 19, 2002Developer: Sonic Team, Dimps
- Adiboo and Paziral's SecretReleased: 2003Developer: Coktel Vision
- Alex the Allegator 4Released: 2003Platforms: Microsoft Windows, macOS, Linux, BeOS, Android
- Pac BrothersReleased: 2003Developer: Skitso Productions
- Prince of Persia: Harem AdventuresReleased: 2003Developer: Gameloft
- Crash Bandicoot 2: N-TrancedReleased: January 7, 2003Series: Crash Bandicoot
- Rockman EXE WSReleased: February 8, 2003Developer: Capcom
- Sonic Mega CollectionReleased: March 7, 2003Developer: Sonic Team
- Tom and Jerry in Infurnal EscapeReleased: March 14, 2003Developer: CinéGroupe
- Tomb Raider: The Osiris CodexReleased: May 1, 2003Series: Tomb Raider
- Super Mario Advance 4: Super Mario Bros. 3Released: July 11, 2003Developer: Nintendo Entertainment Analysis & Development
- Densetsu no Stafy 2Released: September 5, 2003Developer: Tose Co.
- Jak IIReleased: October 14, 2003Developer: Naughty Dog
- Vintergatan: Rädda Jorden!Released: October 22, 2003Publisher: Pan Vision
- Spyro: Attack of the RhynocsReleased: October 27, 2003Genre: isometric platformer, platform game
- Ratchet & Clank: Going CommandoReleased: November 11, 2003Developer: Insomniac Games
- Blob Wars: Metal Blob SolidReleased: December 2003Engine: Simple DirectMedia Layer
- Ozzy & DrixReleased: December 17, 2003Publisher: Midway Games
- Snowy: The Bear's AdventuresReleased: December 22, 2003Developer: Aliasworlds Entertainment
- Adiboo and the Energy ThievesReleased: 2004Developer: Coktel Vision
- Hugo: Cannon CruiseReleased: 2004Developer: Interactive Television Entertainment
- Vic de VitaminevreterReleased: 2004Developer: Netherlands Nutrition Centre
- Vintergatan: Fifunernas återkomst!Released: February 25, 2004Publisher: Pan Vision
- Crayon Shin-chan: Arashi o Yobu - Cinema Land no Daibōken!Released: April 16, 2004Developer: Inti Creates
- Crash Bandicoot Purple: Ripto's Rampage and Spyro Orange: The Cortex ConspiracyReleased: June 3, 2004Series: Crash Bandicoot
- Sonic Advance 3Released: June 7, 2004Developer: Sonic Team, Dimps
- Densetsu no Stafy 3Released: August 5, 2004Developer: Tose Co.
- Crash TwinsanityReleased: August 30, 2004Developer: Traveller's Tales
- Kim Possible 2: Drakken's DemiseReleased: September 15, 2004Publisher: Disney Interactive Studios
- Ratchet & Clank: Up Your ArsenalReleased: November 3, 2004Developer: Insomniac Games
- Spyro: A Hero's TailReleased: November 3, 2004Developer: Eurocom
- Jak 3Released: November 9, 2004Developer: Naughty Dog
- Blinx 2: Masters of Time and SpaceReleased: November 18, 2004Developer: Artoon
- Yoshi Topsy-TurvyReleased: December 9, 2004Developer: Nintendo
- Donkey Kong Jungle BeatReleased: December 16, 2004Developer: Nintendo Entertainment Analysis & Development
- Cave StoryReleased: December 20, 2004Developer: Daisuke Amaya
- Jumper: ReduxReleased: January 3, 2005Platforms: Microsoft Windows
- Yoshi Touch & GoReleased: January 27, 2005Developer: Nintendo Entertainment Analysis & Development
- Caverns of TitanReleased: February 2005Developer: José Luis Tur Santolaria
- Sonic JumpReleased: February 21, 2005Developer: Sonic Team
- Rayman: Hoodlums' RevengeReleased: March 15, 2005Series: Rayman
- Super Monkey Ball DeluxeReleased: March 15, 2005Developer: Amusement Vision
- Kirby: Canvas CurseReleased: March 24, 2005Developer: HAL Laboratory
- Spy vs. SpyReleased: April 6, 2005Developer: Vicious Cycle Software
- Ape Escape 3Released: July 14, 2005Developer: Japan Studio
- Sonic Gems CollectionReleased: August 16, 2005Developer: Sonic Team