- Myth Makers: Trixie in ToylandReleased: August 19, 2005Developer: Data Design Interactive
- Tak: The Great Juju ChallengeReleased: September 19, 2005Developer: Avalanche Software
- Frogger: Ancient ShadowReleased: September 27, 2005Developer: Hudson Soft
- Frogger: Helmet ChaosReleased: September 29, 2005Developer: Konami
- Ty the Tasmanian Tiger 3: Night of the QuinkanReleased: October 11, 2005Developer: Krome Studios
- Spyro: Shadow LegacyReleased: October 18, 2005Developer: Amaze Entertainment
- Super Princess PeachReleased: October 20, 2005Developer: Tose Co.
- Ratchet: DeadlockedReleased: October 25, 2005Developer: Insomniac Games
- Ratchet & Clank: Going MobileReleased: November 2, 2005Developer: Handheld Games
- Kim Possible: KimmunicatorReleased: November 9, 2005Publisher: Disney Interactive Studios
- Sonic RushReleased: November 15, 2005Developer: Sonic Team
- Winx ClubReleased: November 16, 2005Developer: DC Studios
- Athena: Full ThrottleReleased: 2006Developer: SNK
- Bonk's ReturnReleased: 2006Developer: Two Tribes
- Crazy Chicken: Heart of TibetReleased: 2006Developer: Sproing Interactive Media
- Iron ChefReleased: 2006Publisher: Phoenix Games B.V.
- Mega Man X CollectionReleased: January 10, 2006Developer: Capcom
- Pilot Brothers: The Atlantic Herring MysteryReleased: January 27, 2006Developer: Pipe studio
- PsychonautsReleased: February 10, 2006Developer: Double Fine, Budcat Creations
- DaxterReleased: March 14, 2006Developer: Ready at Dawn
- Tomb Raider: LegendReleased: April 7, 2006Developer: Crystal Dynamics
- Densetsu no Stafy 4Released: April 13, 2006Developer: Tose Co.
- New Super Mario Bros.Released: May 15, 2006Developer: Nintendo
- Kim Possible: Legend of the Monkey’s EyeReleased: May 16, 2006Platforms: Microsoft Windows, macOS
- LocoRocoReleased: June 23, 2006Developer: Japan Studio
- Super Monkey Ball AdventureReleased: June 30, 2006Developer: Traveller's Tales
- Saru! Get You! Million MonkeysReleased: July 13, 2006Developer: Sony Interactive Entertainment
- VeggieTales: LarryBoy and the Bad AppleReleased: August 8, 2006Developer: Papaya Studio
- Ultimate Ghosts 'n GoblinsReleased: August 13, 2006Developer: Tose Co.
- Lego Star Wars II: The Original TrilogyReleased: September 12, 2006Developer: Traveller's Tales
- Casper and the Ghostly TrioReleased: September 15, 2006Engine: Havok
- Kirby: Squeak SquadReleased: November 2, 2006Developer: Flagship
- Papa Louie: When Pizzas Attack!Released: November 9, 2006Developer: Flipline Studios
- Yoshi's Island DSReleased: November 13, 2006Developer: Artoon
- Rayman Raving RabbidsReleased: November 14, 2006Platforms: Nintendo DS
- Spider-Man: Battle for New YorkReleased: November 14, 2006Developer: Torus Games
- Super Monkey Ball: Banana BlitzReleased: November 19, 2006Platforms: Wii
- Brave Dwarves: Creeping ShadowsReleased: December 2006Developer: Nival
- Platform RacingReleased: 2007Series: Platform Racing
- TurtixReleased: January 28, 2007Publisher: Big Fish Games
- Ratchet & Clank: Size MattersReleased: February 13, 2007Developer: High Impact Games
- Pilot Brothers: Catch-upReleased: March 2, 2007Publisher: Softclub
- Sonic Mega Collection PlusReleased: March 9, 2007Series: Sonic the Hedgehog
- Bubble Bobble Double ShotReleased: March 23, 2007Series: Bubble Bobble
- ActRaiserReleased: March 27, 2007Developer: Quintet
- Sonic the HedgehogReleased: April 7, 2007Developer: Sonic Team
- Death Jr. and the Science Fair of DoomReleased: May 22, 2007Publisher: Konami
- CrushReleased: May 25, 2007Developer: Kuju Ltd., Zoë Mode
- DK Jungle ClimberReleased: August 9, 2007Developer: Paon DP
- Knytt StoriesReleased: August 30, 2007Developer: Nicklas Nygren
- Drawn to LifeReleased: September 10, 2007Developer: 5th Cell
- Sonic Rush AdventureReleased: September 14, 2007Developer: Sonic Team
- LocoRoco CocorecchoReleased: September 20, 2007Developer: Japan Studio
- Super Paper MarioReleased: September 20, 2007Developer: Intelligent Systems
- Ninjabread ManReleased: September 27, 2007Developer: Data Design Interactive
- SupercowReleased: September 28, 2007Developer: Nevosoft
- Crash of the TitansReleased: October 2, 2007Developer: Radical Entertainment
- Spider-Man: Friend or FoeReleased: October 2, 2007Developer: Next Level Games
- Portal: The Flash VersionReleased: October 9, 2007Engine: Adobe Flash
- Ratchet & Clank Future: Tools of DestructionReleased: October 23, 2007Developer: Insomniac Games
- The Simpsons GameReleased: October 30, 2007Developer: Celbridge
- Nights: Journey of DreamsReleased: December 13, 2007Developer: Sonic Team
- Secret Agent ClankReleased: June 17, 2008Developer: High Impact Games
- Turtix: Rescue AdventureReleased: July 2008Publisher: Big Fish Games
- Wario Land: Shake It!Released: July 24, 2008Developer: Good-Feel
- PixelJunk EdenReleased: July 31, 2008Developer: Q-Games
- Ratchet & Clank Future: Quest for BootyReleased: August 21, 2008Developer: Insomniac Games
- Kirby Super Star UltraReleased: September 22, 2008Developer: HAL Laboratory
- De BlobReleased: September 30, 2008Developer: THQ Nordic, Universomo, Ronimo Games, Blue Tongue Entertainment
- Tak and the Guardians of GrossReleased: October 13, 2008Developer: Blitz Games
- Tak: Mojo MistakeReleased: October 13, 2008Developer: THQ
- LittleBigPlanetReleased: October 27, 2008Developer: Media Molecule
- Crash: Mind over MutantReleased: October 31, 2008Developer: Radical Entertainment
- Skägget i brevlådanReleased: November 6, 2008Developer: Upside Studios
- Prinny: Can I Really Be the Hero?Released: November 20, 2008Developer: Nippon Ichi Software
- Sonic UnleashedReleased: November 27, 2008Developer: Sonic Team
- Prince of Persia: The Fallen KingReleased: December 2, 2008Developer: Ubisoft Casablanca
- KlonoaReleased: December 4, 2008Developer: Paon DP
- Achievement UnlockedReleased: December 17, 2008Developer: John Cooney
- Mr BeanReleased: February 6, 2009Developer: Beyond Reality Games
- Sonic and the Black KnightReleased: March 3, 2009Developer: Sonic Team
- Pitfall: The Lost ExpeditionReleased: March 4, 2009Developer: Edge of Reality
- Giana Sisters DSReleased: April 3, 2009Developer: Spellbound Entertainment
- Doodle JumpReleased: April 6, 2009Developer: Lima Sky
- Chibi-Robo!Released: June 11, 2009Developer: Skip Ltd.
- TrineReleased: July 3, 2009Developer: Frozenbyte
- Dragon Ball: Revenge of King PiccoloReleased: July 23, 2009Developer: Media.Vision
- Okaeri! Chibi-Robo! Happy Richie Ōsōji!Released: July 23, 2009Developer: Skip Ltd.
- Trials HDReleased: August 12, 2009Developer: RedLynx
- Broken Cave RobotReleased: August 30, 2009Platforms: Microsoft Windows
- Hook ChampReleased: October 4, 2009Developer: Rocketcat Games
- Drawn to Life: The Next ChapterReleased: October 8, 2009Developer: 5th Cell
- The Legendary StarfyReleased: October 10, 2009Developer: Tose Co.
- Ratchet & Clank Future: A Crack in TimeReleased: October 27, 2009Developer: Insomniac Games
- Jak and Daxter: The Lost FrontierReleased: November 3, 2009Developer: High Impact Games
- LittleBigPlanetReleased: November 17, 2009Developer: Guerrilla Cambridge
- A Boy and His BlobReleased: November 19, 2009Developer: WayForward Technologies
- Alex Kidd in Shinobi WorldReleased: December 11, 2009Series: Alex Kidd
- Max & the Magic MarkerReleased: January 22, 2010Developer: Press Play
- Toki ToriReleased: January 29, 2010Developer: Two Tribes