| Z Intermediate Global Corporation | Japan | December 13, 2019 | — | — |
| Z-Software | Germany | 2008 | 5 | 1 |
| Zachtronics | United States | 2011 | 6 | 6 |
| Zeiva Inc | — | — | 3 | 3 |
| Zellers | Canada | 1931 | — | 1 |
| Zemina | — | 1981 | — | 1 |
| Zener Works | Japan | July 1990 | 1 | — |
| ZeniMax Media | United States | May 26, 1999 | — | 1 |
| ZeniMax Online Studios | United States | 2007 | 1 | — |
| ZeptoLab | United Kingdom | 2010 | 6 | 5 |
| Zero | Japan | — | 2 | — |
| Zerocreation Games | People's Republic of China | July 2, 2020 | 2 | — |
| Zerodiv | Japan | August 2007 | 10 | — |
| Zerouno Games | Spain | — | 1 | 4 |
| Ziggurat Interactive | United States | — | — | 36 |
| Zima Software | Czech Republic | 1995 | 6 | 3 |
| Zing Games | United States | 2011 | 1 | — |
| Zipper Interactive | United States | 1995 | 9 | — |
| ZlonGame | People's Republic of China | — | 1 | 2 |
| Zoetrope Interactive | — | 2005 | 2 | — |
| Zoink Games | Sweden | 2001 | 2 | 1 |
| Zombie Studios | United States | 1994 | 6 | — |
| Zone | Japan | 1997 | 3 | — |
| Zono | United States | 1991 | 2 | — |
| Zoo Corporation | Japan | April 8, 1986 | 27 | 30 |
| Zoo Digital (United Kingdom) | United Kingdom | — | 1 | — |
| Zoom | Japan | 1988 | 2 | — |
| ZootFly | — | 2002 | 1 | — |
| Zoo Publishing | United States | 2001 | — | 2 |
| Zoë Mode | United Kingdom | 2007 | 9 | — |
| Zushi Games | United Kingdom | 1999 | 1 | 10 |
| Zuxxez Entertainment | Germany | 1994 | — | 2 |
| Zynga | United States | 2007 | 3 | 2 |
| ZyX | Japan | — | 3 | 3 |