| E Frontier | Japan | 1999 | — | 1 |
| EA Bright Light | United Kingdom | 1995 | 4 | — |
| EA Gothenburg | Sweden | 2011 | 4 | — |
| EA Mobile | United States | 2004 | 10 | 4 |
| EA Montreal | Canada | 2004 | 6 | — |
| EA Orlando | United States | 1994 | 49 | — |
| EA Phenomic | Germany | 1997 | 5 | — |
| EA Romania | Romania | 2005 | 3 | — |
| EA Salt Lake | United States | 1992 | 2 | — |
| EA Seattle | United States | 1982 | 1 | — |
| EA Sports | United States | 1991 | 16 | 137 |
| EA Sports Big | United States | 2000 | 2 | 8 |
| EA Vancouver | Canada | 1983 | 96 | — |
| Eagle Dynamics | Russia | 1991 | 3 | — |
| East Japan Railway Company | Japan | April 1987 | — | 1 |
| East Side Games | Canada | 2011 | 2 | — |
| EasyTech | — | 2009 | 1 | — |
| Eat Sleep Play | United States | 2007 | 1 | — |
| Eclipse Games | Spain | — | 6 | 4 |
| Eclipse Software | United States | 1999 | 1 | — |
| Ecole Software | Japan | March 31, 1989 | 2 | 1 |
| Eden Industries | Canada | — | 2 | — |
| Edge Games | United States | 1990 | 1 | 1 |
| Edge of Reality | United States | 1988 | 6 | 1 |
| Edia | Japan | April 9, 1999 | — | 1 |
| Edu-Ware | United States | 1979 | 2 | 2 |
| EGames | United States | 1992 | 1 | 5 |
| Eggcode Games | Germany | 2010 | 1 | 1 |
| EggNut | Canada | 2017 | 2 | — |
| Egmont International Holding | Denmark | September 5, 1984 | — | 2 |
| Egmont Publishing Digital | Denmark | — | 1 | 1 |
| Egosoft | Germany | 1988 | 7 | 1 |
| Eidos Interactive | United Kingdom | 1990 | 1 | 83 |
| Eidos Interactive | United Kingdom | 1988 | 1 | 9 |
| Eidos Montreal | Canada | February 15, 2007 | 9 | — |
| Eighting | Japan | March 15, 1993 | 30 | 1 |
| EightyEight Games | United Kingdom | January 19, 2011 | 2 | 2 |
| Einzelartig Games | Germany | — | 1 | — |
| Eipix Entertainment | — | 2005 | 9 | — |
| Eko Software | France | January 10, 1999 | 11 | — |
| Electric Dreams Software | United Kingdom | 1985 | 1 | 2 |
| Electric Square | United Kingdom | 2015 | 2 | 1 |
| Electro Brain | United States | 1990 | — | 1 |
| Electronic Arts | United States | May 28, 1982 | 66 | 444 |
| Electronic Arts Victor | Japan | 1990 | — | 2 |
| Elemental Games | — | 1999 | 4 | — |
| Elephant Games | — | 2003 | 7 | 2 |
| Elex | People's Republic of China | 2008 | 1 | — |
| ELF Corporation | Japan | April 27, 1989 | 8 | 1 |
| Elf Games | Italy | 2014 | 1 | — |
| Elite Systems | United Kingdom | 1984 | 5 | 3 |
| Elixir Studios | United Kingdom | 1998 | 1 | — |
| Elseware Experience | France | June 16, 2020 | 1 | — |
| Embark Studios | Sweden | November 2018 | 1 | 1 |
| Ember Entertainment | United States | 2011 | 1 | 1 |
| Ember Trail | Sweden | 2017 | 1 | — |
| Embers | France | February 14, 2020 | 1 | 1 |
| Embracer Group | Sweden | 2008 | — | 1 |
| Empire Interactive | United Kingdom | 1987 | 5 | 14 |
| Empty Clip Studios | United States | July 2007 | 3 | — |
| En Masse Entertainment | United States | 2010 | — | 1 |
| Encore, Inc. | United States | 1994 | — | 2 |
| EndlessFluff Games | United States | — | 1 | — |
| Endnight Games | Canada | — | 1 | — |
| Engine Software | Netherlands | 1995 | 20 | 6 |
| English Software | United Kingdom | 1982 | — | 1 |
| Enhance | United States | October 2014 | — | 2 |
| Enix | Japan | 1975 | 6 | 31 |
| EnjoyUp | Spain | — | 6 | 2 |
| Enlight Software | Hong Kong | 1993 | 3 | 4 |
| Enodo Games | France | 2014 | 1 | 1 |
| Ensemble | Japan | — | 2 | — |
| EnsenaSoft | Mexico | — | 21 | 21 |
| Enterbrain | Japan | 2000 | 1 | 6 |
| Entergram | Japan | August 5, 1999 | 1 | 11 |
| Entertainment Software Publishing | Japan | 1997 | 1 | 4 |
| Entex Industries | United States | 1970 | — | 2 |
| Envision Entertainment | Germany | October 8, 2013 | 1 | — |
| Eolith | South Korea | 1996 | — | 2 |
| Epic Llama Games | Argentina | — | 1 | — |
| Epic Records Japan | Japan | August 1978 | — | 2 |
| Epoch | Japan | 1958 | — | 1 |
| Epoch Co. | Japan | May 6, 1958 | 3 | 10 |
| Epsitec SA | Switzerland | 1987 | 16 | 17 |
| Epyx | United States | 1978 | 7 | 7 |
| Erbe Software S.A. | Spain | 1984 | — | 3 |
| ERE Informatique | France | 1983 | 1 | 2 |
| Eremite Games | Poland | — | 1 | — |
| Escu:de | Japan | — | 2 | 2 |
| ESDigital Games | Cyprus | — | — | 2 |
| Espaço Informática | Brazil | 1999 | 1 | — |
| Eternal Alice Studio | Taiwan | June 24, 2019 | 2 | 2 |
| ETH Zurich | Switzerland | October 16, 1855 | — | 1 |
| Etoy | Switzerland | 1994 | 1 | — |
| Etter Studio | Switzerland | 2008 | 1 | 1 |
| Eugen Systems | France | 2000 | 2 | 2 |
| Euphoria Games | Russia | 2019 | 5 | 3 |
| Euphoric Brothers | Canada | — | 5 | 5 |
| Eurocom | United Kingdom | October 1988 | 15 | — |
| Europress | United Kingdom | 1965 | — | 3 |
| Europäisches Hansemuseum | Germany | 2015 | — | 1 |
| Eushully | Japan | 2005 | 10 | 3 |
| Eutechnyx | United Kingdom | 1987 | 3 | — |
| EV Interactive | United States | — | 2 | 1 |
| Eversim | France | 2004 | 4 | — |
| Evil Empire | France | January 31, 2019 | 4 | — |
| Evil Twin Artworks | United Kingdom | — | 1 | — |
| Evolution Studios | United Kingdom | 1999 | 6 | — |
| Evryware | United States | 1980 | 3 | — |
| ExA-Arcadia | Singapore | 2019 | 1 | 1 |
| Exakt Entertainment | United States | 1999 | 3 | — |
| Examu | Japan | 2007 | 7 | 4 |
| Excalibur Games | United Kingdom | March 14, 1997 | — | 1 |
| Excalibur Publishing | United Kingdom | — | — | 5 |
| Excellent Rectangle | Canada | October 2020 | 1 | 1 |
| Excite | United States | 1994 | — | — |
| ExDream | Germany | — | 1 | — |
| Exe-Create | Japan | — | 23 | 1 |
| Executive Office of the President of the United States | United States | 1939 | — | 5 |
| Exidy | United States | 1974 | 1 | — |
| Exient Entertainment | United Kingdom | 2001 | 1 | — |
| EXNOA | Japan | December 13, 2017 | 2 | 2 |
| Expansive Worlds | Sweden | — | 2 | — |
| Experience | Japan | April 2007 | 3 | 1 |
| Explosm | United States | 2009 | 1 | — |
| Exponential Games | Canada | — | 1 | 1 |
| Extremely OK Games | Canada | April 16, 2018 | 2 | — |
| Eyedentity Games | — | 2007 | 1 | 1 |
| Étranges Libellules | France | 1994 | 4 | — |