| Close Combat: First to Fight | April 6, 2005 | Destineer | Close Combat |
| Stronghold 2 | April 18, 2005 | Firefly Studios | Stronghold |
| NBA 2K6 | September 26, 2005 | Visual Concepts | NBA 2K |
| Vietcong 2 | October 24, 2005 | Pterodon | — |
| The Elder Scrolls IV: Oblivion | March 20, 2006 | 4J Studios, Superscape, Bethesda Game Studios | — |
| CivCity: Rome | July 24, 2006 | Firaxis Games, Firefly Studios | — |
| Stronghold Legends | October 13, 2006 | Firefly Studios | Stronghold |
| Sid Meier's Railroads! | October 17, 2006 | Firaxis Games | — |
| Dungeon Siege: Throne of Agony | October 30, 2006 | SuperVillain Studios | — |
| The Darkness | June 25, 2007 | Starbreeze Studios | — |
| BioShock | August 21, 2007 | Irrational Games | BioShock |
| Civilization Revolution | June 13, 2008 | Firaxis Games | — |
| Civilization IV: Colonization | September 23, 2008 | Firaxis Games | — |
| Carnival Games: Mini-Golf | October 31, 2008 | Cat Daddy Games | Carnival Games |
| Borderlands | October 20, 2009 | Gearbox Software, Feral Interactive | Borderlands |
| The Backyardigans | October 26, 2009 | Black Lantern Studios, Inc. | — |
| BioShock 2 | February 9, 2010 | 2K Marin | BioShock |
| Mafia II | August 27, 2010 | — | Mafia |
| Jimmy's Vendetta | September 7, 2010 | — | Mafia |
| Duke Nukem Forever | June 10, 2011 | 3D Realms | — |
| Civilization World | July 6, 2011 | Firaxis Games | — |
| The Darkness II | February 7, 2012 | Digital Extremes | — |
| Spec Ops: The Line | June 26, 2012 | Darkside Game Studios | Spec Ops |
| XCOM: Enemy Unknown | October 9, 2012 | Feral Interactive, Firaxis Games | X-COM |
| Borderlands Legends | October 31, 2012 | 2K China | Borderlands |
| BioShock Infinite | March 26, 2013 | Aspyr, Irrational Games, 2K | BioShock |
| Borderlands 2: Tiny Tina's Assault on Dragon Keep | June 25, 2013 | Gearbox Software | Borderlands |
| The Bureau: XCOM Declassified | August 20, 2013 | 2K Marin | X-COM |
| 2K Drive | September 5, 2013 | Lucid Games | 2K Drive |
| BioShock Infinite: Burial at Sea | November 12, 2013 | Irrational Games | BioShock |
| Borderlands 2 | May 13, 2014 | Gearbox Software, Iron Galaxy Studios, Aspyr | Borderlands |
| Civilization Revolution 2 | July 2, 2014 | Firaxis Games | — |
| Borderlands: The Pre-Sequel | October 17, 2014 | Gearbox Software, 2K Australia, Aspyr | Borderlands |
| Borderlands: The Handsome Collection | March 27, 2015 | Gearbox Software, Iron Galaxy Studios | Borderlands |
| WWE 2K | July 16, 2015 | Visual Concepts, N-Space | WWE 2K |
| XCOM 2 | February 5, 2016 | Feral Interactive, Firaxis Games | X-COM |
| BioShock 2 Remastered | September 15, 2016 | 2K Marin, Digital Extremes, 2K Australia, 2K China, Blind Squirrel Entertainment, Feral Interactive | — |
| BioShock Remastered | September 15, 2016 | 2K Australia, Blind Squirrel Entertainment, Irrational Games, Feral Interactive | BioShock |
| Mafia III | October 7, 2016 | Aspyr | Mafia |
| Civilization VI | October 21, 2016 | Firaxis Games | — |
| NBA 2K18 | September 19, 2017 | Visual Concepts | NBA 2K |
| Civilization VI: Rise and Fall | February 8, 2018 | Firaxis Games | — |
| Borderlands: Game of the Year Edition Enhanced | April 3, 2019 | Gearbox Software, Blind Squirrel Entertainment | Borderlands |
| Borderlands 3 | September 13, 2019 | Gearbox Software | Borderlands |
| XCOM: Chimera Squad | April 24, 2020 | Firaxis Games | X-COM |
| Mafia II: Definitive Edition | May 19, 2020 | — | Mafia |
| Mafia III: Definitive Edition | May 19, 2020 | — | Mafia |
| Mafia: Trilogy | May 19, 2020 | — | Mafia |
| Borderlands Legendary Collection | May 28, 2020 | — | Borderlands |
| Mafia: Definitive Edition | September 25, 2020 | — | Mafia |
| NBA 2K22 | September 10, 2021 | Visual Concepts | NBA 2K |
| NBA 2K22 Arcade Edition | October 19, 2021 | — | NBA 2K |
| Tiny Tina's Assault on Dragon Keep: A Wonderlands One-shot Adventure | November 9, 2021 | Gearbox Software, Stray Kite Studios | — |
| WWE 2K22 | March 11, 2022 | Visual Concepts | WWE 2K |
| Tiny Tina's Wonderlands | March 25, 2022 | Gearbox Software | Borderlands |
| The Quarry | June 10, 2022 | — | — |
| NBA 2K23 | September 8, 2022 | Visual Concepts | NBA 2K |
| PGA Tour 2K23 | October 14, 2022 | HB Studios | PGA Tour 2K |
| New Tales from the Borderlands | October 21, 2022 | Gearbox Software | Borderlands |
| Midnight Suns | December 2, 2022 | Firaxis Games | — |