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34,989 games
- TrackMania NationsReleased: 2006Developer: Nadeo
- WestwardReleased: 2006Developer: Sandlot Games
- Whirlwind over VietnamReleased: 2006Publisher: Evolved Games
- Who Wants To Be A Millionaire: Family Entertainment EditionReleased: 2006Developer: Zoo Digital (United Kingdom)
- Wings 2Released: 2006Platforms: Linux
- Winter SportsReleased: 2006Publisher: Oxygen Games
- WolfschanzeReleased: 2006
- Yoomurjak's RingReleased: 2006Developer: Pierrot
- Ys V: Lost Kefin, Kingdom of SandReleased: 2006Developer: Access
- Taito Memories PocketReleased: January 5, 2006Series: Taito Memories
- Kidz Sports BasketballReleased: January 6, 2006Developer: Data Design Interactive
- Mega Man X CollectionReleased: January 10, 2006Developer: Capcom
- Gunparade Orchestra: Shiro no ShōReleased: January 12, 2006Developer: Alfa System
- Snowy: Treasure Hunter 2Released: January 13, 2006Developer: Aliasworlds Entertainment
- 25 to LifeReleased: January 17, 2006Developer: Avalanche Software
- Diner Dash 2: Restaurant RescueReleased: January 18, 2006Developer: Alawar Entertainment
- Iron FeatherReleased: January 19, 2006Developer: Konami
- Gore Screaming ShowReleased: January 20, 2006Publisher: JAST USA
- Torino 2006Released: January 24, 2006Publisher: 2K Sports
- Ar Tonelico: Melody of ElemiaReleased: January 26, 2006Developer: Gust Co. Ltd.
- Bleach: The Blade of FateReleased: January 26, 2006Developer: Treasure
- Dirge of Cerberus: Final Fantasy VIIReleased: January 26, 2006Developer: Square Enix
- English Training: Have Fun Improving Your Skills!Released: January 26, 2006Developer: Nintendo Software Planning & Development
- Onimusha: Dawn of DreamsReleased: January 26, 2006Developer: Capcom
- Evil Islands: Lost in AstralReleased: January 27, 2006Publisher: Nival
- Futari de Hitotsu no KoigokoroReleased: January 27, 2006Platforms: Microsoft Windows
- Maid-san★Spirits! ~Watashi no Naka ni Iru Anata~Released: January 27, 2006Platforms: Microsoft Windows
- Pilot Brothers: The Atlantic Herring MysteryReleased: January 27, 2006Developer: Pipe studio
- Days of Memories 2: Boku no Ichiban Taisetsu na Kimi eReleased: February 2006Country of origin: Japan
- Pump It Up ZeroReleased: February 1, 2006Series: Pump It Up
- Heroes of Malgrimia: The Lost World of MagicReleased: February 2, 2006Publisher: Noviy Disk
- Tourist TrophyReleased: February 2, 2006Developer: Polyphony Digital
- HimemikoReleased: February 3, 2006Series: Himemiko
- Forbidden Siren 2Released: February 9, 2006Developer: Japan Studio, Project Siren
- Zombie VirusReleased: February 9, 2006Publisher: D3 Publisher
- Gakuen Alice: Kira Kira Memory KissReleased: February 10, 2006Genre: adventure video game
- Lil cal 64Released: February 10, 2006Developer: Pseudo Interactive
- PsychonautsReleased: February 10, 2006Developer: Double Fine, Budcat Creations
- Age of Empires: The Age of KingsReleased: February 14, 2006Publisher: Majesco Entertainment
- Empire Earth II: The Art of SupremacyReleased: February 14, 2006Developer: Rockstar New England
- Midway Arcade Treasures Deluxe EditionReleased: February 15, 2006Developer: Midway Games
- Nicktoons Winners Cup RacingReleased: February 15, 2006Publisher: Cosmi Corporation
- Dance Dance Revolution StrikeReleased: February 16, 2006Developer: Konami
- Monster Hunter 2Released: February 16, 2006Developer: Capcom
- Fight Night Round 3Released: February 20, 2006Developer: Electronic Arts Chicago
- Initial D: Street StageReleased: February 20, 2006Platforms: PlayStation Portable
- Galactic Civilizations II: Dread LordsReleased: February 21, 2006Developer: Stardock
- Sonic RidersReleased: February 21, 2006Developer: Sonic Team
- Baten Kaitos OriginsReleased: February 23, 2006Developer: Tri-Crescendo
- CrashdayReleased: February 23, 2006Developer: Replay Studios
- Disgaea 2Released: February 23, 2006Developer: Nippon Ichi Software
- Fantasy Earth: ZeroReleased: February 23, 2006Publisher: GMO Gamepot
- Namco Museum Vol.2Released: February 23, 2006Developer: Tose Co., Gotch Technology Corp.
- Naval Ops: Warship Gunner 2Released: February 23, 2006Developer: Koei
- Separate HeartsReleased: February 23, 2006Genre: visual novel
- Suikoden VReleased: February 23, 2006Developer: Konami
- Yu-Gi-Oh! Duel Monsters Expert 2006Released: February 23, 2006Country of origin: Japan
- Angel BreathReleased: February 24, 2006Developer: Giga
- AR: Wasurerareta NatsuReleased: February 24, 2006Developer: Circus
- Boy Meets GirlReleased: February 24, 2006Developer: Front Wing
- Metal Slug 6Released: February 24, 2006Developer: SNK
- Muv-Luv AlternativeReleased: February 24, 2006Developer: Âge
- MX vs. ATV: On the EdgeReleased: February 27, 2006Developer: Rainbow Studios
- 24: The GameReleased: February 28, 2006Developer: Guerrilla Cambridge
- Dungeons & Dragons OnlineReleased: February 28, 2006Developer: WB Games Boston
- Final Fight: StreetwiseReleased: February 28, 2006Developer: Capcom
- MLB 06: The ShowReleased: February 28, 2006Developer: San Diego Studio
- SWAT ForceReleased: February 28, 2006Series: SWAT
- The Rose ChroniclesReleased: March 2006Engine: RPG Maker 2003
- Tokimeki Memorial OnlineReleased: March 2006Developer: Konami
- Bitva Geroev 2: Ekho VoinyReleased: March 2, 2006Developer: BloodLine
- Children of ManaReleased: March 2, 2006Developer: Square Enix
- Mobile Suit Gundam Climax U.C.Released: March 2, 2006Genre: action game
- Valkyrie Profile: LennethReleased: March 2, 2006Developer: Tri-Ace
- Maximum-FootballReleased: March 3, 2006Publisher: Matrix Games
- Tales of Eternia OnlineReleased: March 3, 2006Developer: Namco
- Sakura Wars 2: Thou Shalt Not DieReleased: March 9, 2006Developer: Sega Wow, Red Entertainment
- The Legend of Heroes: Trails in the Sky SCReleased: March 9, 2006Publisher: Ghostlight, Xseed Games
- Tom Clancy's Ghost Recon Advanced WarfighterReleased: March 9, 2006Developer: Ubisoft Paris
- Heracles: Battle with the GodsReleased: March 10, 2006Developer: Neko Entertainment
- DaxterReleased: March 14, 2006Developer: Ready at Dawn
- Driver: Parallel LinesReleased: March 14, 2006Developer: Ubisoft Reflections
- Neopets: Petpet Adventures: The Wand of WishingReleased: March 14, 2006Developer: Santa Monica Studio
- Beatmania IIDX 13: DistortedReleased: March 15, 2006Developer: Konami
- Final Fantasy XIIReleased: March 16, 2006Developer: Square Enix
- Keroro Gunso: Enshū da Yo! Zenin ShūgōReleased: March 16, 2006Developer: Bandai
- Buzz!: The BIG QuizReleased: March 17, 2006Publisher: Sony Interactive Entertainment
- Dancing Stage Unleashed 3Released: March 17, 2006Developer: Konami
- KeepsakeReleased: March 17, 2006Publisher: The Adventure Company
- Romance of the Three Kingdoms XIReleased: March 17, 2006Developer: Koei
- SeafightReleased: March 18, 2006Developer: Bigpoint GmbH
- Refuse: Home Sweep HomeReleased: March 20, 2006Platforms: Microsoft Windows
- The Elder Scrolls IV: OblivionReleased: March 20, 2006Developer: 4J Studios, Superscape, Bethesda Game Studios
- CMT Presents: Karaoke Revolution CountryReleased: March 21, 2006Developer: Harmonix Music Systems
- Territory WarReleased: March 21, 2006Developer: Shawn Tanner
- The GodfatherReleased: March 21, 2006Developer: Visceral Games
- Tom Clancy's Splinter Cell: EssentialsReleased: March 21, 2006Series: Tom Clancy's Splinter Cell
- CatzReleased: March 22, 2006Developer: MTO
- Worms: Open WarfareReleased: March 22, 2006Developer: Team17
- Ace Combat Zero: The Belkan WarReleased: March 23, 2006Developer: Namco