- The Idolmaster 2Released: February 24, 2011Developer: Bandai Namco Entertainment
- Fight Night ChampionReleased: March 1, 2011Developer: EA Vancouver
- Way of the Samurai 4Released: March 3, 2011Developer: Acquire
- Dragon Age IIReleased: March 8, 2011Developer: Bioware
- MLB 11: The ShowReleased: March 8, 2011Developer: San Diego Studio
- Dynasty Warriors 7Released: March 10, 2011Developer: Koei Tecmo Holdings
- HomefrontReleased: March 15, 2011Developer: Digital Extremes, Kaos Studios
- Top Spin 4Released: March 15, 2011Publisher: 2K Sports
- MotorStorm: ApocalypseReleased: March 16, 2011Developer: Evolution Studios
- Ghostbusters: Sanctum of SlimeReleased: March 23, 2011Developer: Wanako Studios
- Crysis 2Released: March 25, 2011Series: Crysis
- Back to the Future: The Game - Episode 3: Citizen BrownReleased: March 29, 2011Developer: Telltale Games
- Shift 2 UnleashedReleased: March 29, 2011Developer: Slightly Mad Studios
- WWE All StarsReleased: March 29, 2011Developer: THQ
- Lego Star Wars III: The Clone WarsReleased: March 30, 2011Developer: Traveller's Tales
- Tiger Woods PGA Tour 12Released: April 1, 2011Developer: EA Orlando
- Arcana Heart 3Released: April 19, 2011Developer: Examu
- Mortal KombatReleased: April 19, 2011Developer: NetherRealm Studios
- SOCOM 4 U.S. Navy SEALsReleased: April 19, 2011Developer: Zipper Interactive
- AFL LiveReleased: April 21, 2011Developer: Big Ant Studios
- Operation Flashpoint: Red RiverReleased: April 21, 2011Developer: Codemasters
- Thor: God of ThunderReleased: April 28, 2011Developer: Liquid Entertainment
- BrinkReleased: May 10, 2011Developer: Splash Damage
- Lego Pirates of the CaribbeanReleased: May 10, 2011Developer: Traveller's Tales
- MX vs. ATV AliveReleased: May 10, 2011Developer: Rainbow Studios
- Virtua Tennis 4Released: May 10, 2011Series: Virtua Tennis
- BlazBlue: Continuum Shift IIReleased: May 12, 2011Developer: Arc System Works
- Chrono TriggerReleased: May 16, 2011Developer: Square
- Red Faction: ArmageddonReleased: June 7, 2011Series: Red Faction
- InFamous 2Released: June 9, 2011Series: InFamous
- Yakuza: Dead SoulsReleased: June 9, 2011Series: Yakuza
- Duke Nukem ForeverReleased: June 10, 2011Developer: 3D Realms
- Child of EdenReleased: June 14, 2011Developer: Q Entertainment
- Sengoku Hime 3: Tenka o Kirisaku Hikari to KageReleased: June 17, 2011Publisher: Unicorn-A, SystemSoft Alpha
- Dungeon Siege IIIReleased: June 21, 2011Developer: Obsidian Entertainment
- F.E.A.R. 3Released: June 21, 2011Publisher: Warner Bros. Games
- Atelier Meruru: The Apprentice of ArlandReleased: June 23, 2011Developer: Gust Co. Ltd.
- Back to the Future: The Game - Episode 5: OUTATIMEReleased: June 23, 2011Platforms: PlayStation 3, Microsoft Windows
- Bleach: Soul ResurrecciónReleased: June 23, 2011Developer: Japan Studio
- Earth Defense Force: Insect ArmageddonReleased: July 5, 2011Developer: Vicious Cycle Software
- Harry Potter and the Deathly Hallows – Part 2Released: July 14, 2011Developer: EA Bright Light
- Shin Koihime Musou ~Fighting Maidens of the Romance of the Three Kingdoms~Released: July 30, 2011Developer: Rain Entertainment
- Monochrome RacingReleased: August 2, 2011Developer: Nordcurrent
- Hyperdimension Neptunia Mk2Released: August 18, 2011Developer: Idea Factory
- Deus Ex: Human RevolutionReleased: August 23, 2011Developer: Eidos Montreal
- Driver: San FranciscoReleased: August 30, 2011Developer: Ubisoft Reflections
- Elevator Action DeluxeReleased: August 30, 2011Developer: Taito
- Madden NFL 12Released: August 30, 2011Developer: EA Orlando
- Mortal Kombat Arcade KollectionReleased: August 31, 2011Developer: NetherRealm Studios
- Resistance 3Released: September 6, 2011Developer: Insomniac Games
- Warhammer 40,000: Space MarineReleased: September 6, 2011Series: Warhammer 40,000: Space Marine
- NHL 12Released: September 8, 2011Developer: EA Vancouver
- Tales of XilliaReleased: September 8, 2011Developer: Namco Tales Studio
- God of War: Origins CollectionReleased: September 13, 2011Platforms: PlayStation 3
- Tekken Tag Tournament 2Released: September 14, 2011Developer: Bandai Namco Entertainment
- The Penguins of Madagascar: Dr. Blowhole Returns – Again!Released: September 16, 2011Developer: Griptonite Games
- Burnout Crash!Released: September 20, 2011Developer: Criterion Games
- F1 2011Released: September 20, 2011Developer: Sumo Digital
- Jetpack JoyrideReleased: September 20, 2011Developer: Halfbrick Studios
- FIFA 12Released: September 27, 2011Developer: EA Vancouver
- Worms Ultimate MayhemReleased: September 28, 2011Developer: Team17
- Air Conflicts: Secret WarsReleased: September 30, 2011Developer: Farming Simulator, 3Division
- NBA 2K12Released: October 4, 2011Developer: Visual Concepts, Virtuos
- RageReleased: October 4, 2011Series: Rage
- Ra.One: The GameReleased: October 5, 2011Platforms: PlayStation 3
- Just Dance 3Released: October 7, 2011Developer: Ubisoft Paris
- Dead Rising 2: Off the RecordReleased: October 11, 2011Developer: Capcom Vancouver
- Call of Juarez: The CartelReleased: October 13, 2011Series: Call of Juarez
- Pro Evolution Soccer 2012Released: October 14, 2011Developer: Konami
- Skylanders: Spyro's AdventureReleased: October 14, 2011Developer: Toys for Bob
- Batman: Arkham CityReleased: October 18, 2011Developer: WB Games Montréal, Rocksteady Studios, Iron Galaxy Studios, Virtuos, Feral Interactive
- Dungeon DefendersReleased: October 18, 2011Developer: Chromatic Games
- Payday: The HeistReleased: October 18, 2011Developer: Overkill Software
- Ratchet & Clank: All 4 OneReleased: October 18, 2011Developer: Insomniac Games
- RocksmithReleased: October 18, 2011Developer: Ubisoft San Francisco
- Arcania: Fall of SetarrifReleased: October 25, 2011Developer: Spellbound Entertainment
- Infamous: Festival of BloodReleased: October 25, 2011Series: InFamous
- Just Dance Kids 2Released: October 25, 2011Developer: Land Ho!
- PixelJunk SideScrollerReleased: October 25, 2011Developer: Q-Games
- Hasbro Family Game Night 4: The Game ShowReleased: November 1, 2011Developer: EA Salt Lake, Wahoo Studios
- Sonic GenerationsReleased: November 1, 2011Developer: Sonic Team
- Uncharted 3: Drake's DeceptionReleased: November 1, 2011Developer: Naughty Dog
- Battlefield 3Released: November 2, 2011Developer: DICE
- Call of Duty: Modern Warfare 3Released: November 8, 2011Developer: Raven Software, Sledgehammer Games, Treyarch, Infinity Ward
- Sengoku Basara 3 UtageReleased: November 10, 2011Developer: Capcom
- Assassin's Creed: RevelationsReleased: November 15, 2011Engine: Ubisoft Anvil
- EyePet & FriendsReleased: November 15, 2011Developer: London Studio
- Marvel Super Hero Squad: Comic CombatReleased: November 15, 2011Developer: Griptonite Games
- Saints Row: The ThirdReleased: November 15, 2011Publisher: THQ
- Super Star KartzReleased: November 15, 2011Developer: High Impact Games
- Ultimate Marvel vs. Capcom 3Released: November 15, 2011Developer: Capcom, Eighting
- Ni no Kuni: Wrath of the White WitchReleased: November 17, 2011Developer: Level-5
- Heavy Fire: AfghanistanReleased: November 18, 2011Publisher: Mastiff
- Lego Harry Potter: Years 5–7Released: November 18, 2011Developer: Traveller's Tales
- MotorStorm: RCReleased: November 22, 2011Developer: Evolution Studios
- Serious Sam 3: BFEReleased: November 22, 2011Developer: Croteam
- Saint Seiya SenkiReleased: November 23, 2011Developer: Dimps
- Rayman OriginsReleased: November 24, 2011Series: Rayman
- GoldenEye 007Released: November 25, 2011Developer: Eurocom
- WWE '12Released: November 25, 2011Developer: Yuke's