- Escape from Monkey IslandReleased: November 8, 2000Developer: Lucasfilm Games
- The Operative: No One Lives ForeverReleased: December 8, 2000Developer: Monolith Productions
- Spy Fox: Hold the MustardReleased: December 31, 2000Developer: Humongous Entertainment
- Adiboo 3Released: 2001Developer: Coktel Vision
- Pixeline: Fuld af fis og balladeReleased: 2001Developer: Studio 1-2
- Planet Hot WheelsReleased: 2001Developer: Mattel
- The Oregon Trail 4th EditionReleased: 2001Developer: Minnesota Educational Computing Consortium
- Zoombinis: Mountain RescueReleased: 2001Developer: The Learning Company, Technical Education Research Centers
- RuneScapeReleased: January 4, 2001Developer: Jagex
- Clive Barker's UndyingReleased: February 21, 2001Developer: Danger Close Games
- Black & WhiteReleased: March 25, 2001Developer: Lionhead Studios
- Spy Fox 3: "Operation Ozone"Released: March 30, 2001Developer: Humongous Entertainment
- Desperados: Wanted Dead or AliveReleased: April 20, 2001Developer: Spellbound Entertainment
- TropicoReleased: April 21, 2001Developer: PopTop Software, Feral Interactive
- Myst III: ExileReleased: May 8, 2001Developer: Presto Studios
- BejeweledReleased: May 30, 2001Series: Bejeweled
- Half-Life: Blue ShiftReleased: June 12, 2001Developer: Gearbox Software
- Freddi Fish 5: The Case of the Creature of Coral CoveReleased: June 19, 2001Developer: Humongous Entertainment
- Diablo II: Lord of DestructionReleased: June 27, 2001Developer: Blizzard North
- Commandos 2: Men of CourageReleased: September 20, 2001Developer: Pyro Studios
- Zoo TycoonReleased: October 17, 2001Developer: Blue Fang Games
- Grand Theft Auto IIIReleased: October 23, 2001Series: Grand Theft Auto
- Tony Hawk's Pro Skater 3Released: October 28, 2001Developer: Gearbox Software, Shaba Games, Edge of Reality, HotGen, Neversoft
- Age of Empires II: Gold EditionReleased: October 31, 2001Developer: MacSoft Games
- Star Wars: Galactic BattlegroundsReleased: November 13, 2001Developer: Lucasfilm Games
- Tom Clancy's Ghost ReconReleased: November 13, 2001Developer: Red Storm Entertainment
- Harry Potter and the Philosopher's StoneReleased: November 15, 2001Developer: MacSoft Games, KnowWonder
- Oddworld: Munch's OddyseeReleased: November 15, 2001Developer: Oddworld Inhabitants
- Wizardry 8Released: November 15, 2001Developer: Sir-Tech
- Harry Potter and the Philosopher's StoneReleased: November 16, 2001Developer: KnowWonder
- Baldur's Gate: Dark AllianceReleased: December 3, 2001Developer: High Voltage Software, Snowblind Studios
- Europa Universalis IIReleased: December 11, 2001Developer: Development Studio
- Max PayneReleased: December 12, 2001Series: Max Payne
- Dieselråttor & sjömansmöss: Jakten på SolkattenReleased: 2002Developer: PennFilm Studio AB
- Gridrunner++Released: 2002Developer: Jeff Minter
- Pixeline: Kong GulerodReleased: 2002Developer: Studio 1-2
- SyberiaReleased: January 9, 2002Series: Syberia
- Black & White: Creature IsleReleased: January 22, 2002Developer: Lionhead Studios
- Medal of Honor: Allied AssaultReleased: January 22, 2002Developer: 2015, Inc.
- Worms BlastReleased: March 22, 2002Developer: Team17
- Star Wars Jedi Knight II: Jedi OutcastReleased: March 26, 2002Developer: Raven Software
- Dungeon SiegeReleased: April 5, 2002Developer: Wargaming Seattle
- Zoo Tycoon: Dinosaur DigsReleased: May 19, 2002Developer: Blue Fang Games
- Soldier of Fortune II: Double HelixReleased: May 20, 2002Developer: Raven Software
- Warcraft III: Reign of ChaosReleased: July 3, 2002Developer: Blizzard Entertainment
- Law & Order: Dead on the MoneyReleased: September 24, 2002Developer: Legacy Interactive
- No One Lives Forever 2: A Spy in H.A.R.M.'s WayReleased: September 30, 2002Developer: Monolith Productions
- Unreal Tournament 2003Released: October 1, 2002Series: Unreal
- Tony Hawk's Pro Skater 4Released: October 23, 2002Developer: Neversoft
- Bridge Construction SetReleased: October 26, 2002Developer: Chronic Logic
- Grand Theft Auto: Vice CityReleased: October 29, 2002Series: Grand Theft Auto
- MathicaReleased: November 4, 2002Developer: Braingame Publishing
- Harry Potter and the Chamber of SecretsReleased: November 5, 2002Developer: KnowWonder
- Age of MythologyReleased: November 11, 2002Developer: SkyBox Labs
- Medal of Honor: Allied Assault - SpearheadReleased: November 12, 2002Series: Medal of Honor
- Tom Clancy's Splinter CellReleased: November 17, 2002Series: Tom Clancy's Splinter Cell
- James Bond 007: NightfireReleased: November 18, 2002Developer: Eurocom
- Hearts of IronReleased: November 24, 2002Developer: Development Studio
- LuxReleased: November 25, 2002Developer: Sillysoft Games
- Alex the Allegator 4Released: 2003Platforms: Microsoft Windows, macOS, Linux, BeOS, Android
- Bygg hus med Mulle MeckReleased: 2003Developer: Gravity e-learning
- Massive AssaultReleased: 2003Developer: Wargaming
- Pixeline: I det Vilde WestenReleased: 2003Developer: Studio 1-2
- SamorostReleased: 2003Developer: Jakub Dvorský
- Star Wars: Knights of the Old RepublicReleased: 2003Developer: Bioware
- Victoria: An Empire Under the SunReleased: 2003Developer: Development Studio
- SimCity 4Released: January 14, 2003Developer: Maxis
- Rayman 3: Hoodlum HavocReleased: February 21, 2003Developer: Ubisoft Shanghai
- Master of Orion IIIReleased: February 25, 2003Developer: Quicksilver Software
- Tom Clancy's Rainbow Six 3: Raven ShieldReleased: March 18, 2003Developer: Ubisoft Milan, Red Storm Entertainment
- Delta Force: Black Hawk DownReleased: March 24, 2003Platforms: Microsoft Windows, macOS
- Lunar JetmanReleased: April 2003Platforms: Microsoft Windows, macOS
- Tropico 2: Pirate CoveReleased: April 8, 2003Developer: Frog City Software
- Postal 2Released: April 14, 2003Developer: Running with Scissors
- RHEMReleased: May 10, 2003Publisher: Got Game Entertainment
- Rise of NationsReleased: May 20, 2003Developer: Big Huge Games
- Wolfenstein: Enemy TerritoryReleased: May 29, 2003Developer: Splash Damage
- Star Trek: Elite Force IIReleased: June 20, 2003Developer: Ritual Entertainment
- Tomb Raider: The Angel of DarknessReleased: June 20, 2003Developer: Core Design
- Neverwinter Nights: Shadows of UndrentideReleased: June 21, 2003Developer: Floodgate Entertainment
- Second LifeReleased: June 23, 2003Developer: Linden Lab
- Street Legal Racing: RedlineReleased: July 18, 2003Developer: Invictus Games
- Geneforge 2Released: July 25, 2003Developer: Spiderweb Software
- Neverwinter NightsReleased: August 5, 2003Developer: Bioware
- Battlefield 1942: Secret Weapons of WWIIReleased: September 4, 2003Developer: DICE
- Star Wars Jedi Knight: Jedi AcademyReleased: September 17, 2003Developer: Raven Software
- SimCity 4: Rush HourReleased: September 22, 2003Developer: Maxis
- Ford Racing 2Released: October 23, 2003Developer: Razorworks
- Railroad Tycoon 3Released: October 27, 2003Developer: PopTop Software
- Håkan BråkanReleased: November 5, 2003Developer: Upside Studios
- Uru: Ages Beyond MystReleased: November 11, 2003Developer: Cyan Worlds
- Championship Manager: Season 03/04Released: November 21, 2003Developer: Sports Interactive
- XIIIReleased: November 25, 2003Developer: Ubisoft Paris
- Blob Wars: Metal Blob SolidReleased: December 2003Engine: Simple DirectMedia Layer
- Neverwinter Nights: Hordes of the UnderdarkReleased: December 2, 2003Developer: Bioware
- X2: The ThreatReleased: December 3, 2003Developer: Egosoft
- ZumaReleased: December 12, 2003Developer: Oberon Media
- Postal 2: Share the PainReleased: December 17, 2003Developer: Resurrection Studios
- Snowy: The Bear's AdventuresReleased: December 22, 2003Developer: Aliasworlds Entertainment
- Allrams höjdarspelReleased: 2004Developer: Upside Studios