- Pro Evolution Soccer 2009Released: October 17, 2008Developer: Konami
- Midnight Club: Los AngelesReleased: October 20, 2008Series: Midnight Club
- Far Cry 2Released: October 21, 2008Series: Far Cry
- LittleBigPlanetReleased: October 27, 2008Developer: Media Molecule
- Command & Conquer: Red Alert 3Released: October 28, 2008Developer: Danger Close Games
- Wipeout HDReleased: October 29, 2008Developer: SCE Studio Liverpool
- MotoGP '08Released: October 30, 2008Developer: Milestone S.r.l.
- Inferno PoolReleased: November 2008Developer: Dark Energy Digital
- Valkyrie Profile: Covenant of the PlumeReleased: November 1, 2008Developer: Tri-Ace
- Madagascar: Escape 2 AfricaReleased: November 4, 2008Developer: Toys for Bob
- Naruto: Ultimate Ninja StormReleased: November 4, 2008Developer: CyberConnect2
- Resistance 2Released: November 4, 2008Developer: Insomniac Games
- The Legend of Spyro: Dawn of the DragonReleased: November 5, 2008Developer: The Mighty Troglodytes, Étranges Libellules
- WWE SmackDown vs. Raw 2009Released: November 6, 2008Developer: Yuke's
- Guitar Hero World TourReleased: November 7, 2008Developer: Neversoft
- Call of Duty: World at WarReleased: November 11, 2008Developer: Treyarch, Exakt Entertainment, Arkane Studios
- NHL 2K9Released: November 14, 2008Developer: Visual Concepts
- SingStar: ABBAReleased: November 14, 2008Developer: London Studio
- AC/DC Live: Rock Band Track PackReleased: November 16, 2008Developer: Harmonix Music Systems
- Mortal Kombat vs. DC UniverseReleased: November 16, 2008Developer: Midway Games
- NCAA Basketball '09Released: November 17, 2008Developer: EA Vancouver
- Alone in the DarkReleased: November 18, 2008Series: Alone in the Dark
- Karaoke Revolution Presents: American Idol Encore 2Released: November 18, 2008Developer: Blitz Games Studios
- Kingdom Hearts CodedReleased: November 18, 2008Developer: Square Enix
- Tomb Raider: UnderworldReleased: November 18, 2008Developer: Crystal Dynamics
- BlazBlue: Calamity TriggerReleased: November 19, 2008Developer: Arc System Works
- Hasbro Family Game NightReleased: November 20, 2008Developer: Electronic Arts
- Need for Speed: UndercoverReleased: November 20, 2008Series: Need for Speed
- Baddest of the BandsReleased: November 21, 2008Developer: Telltale Games
- Super Street Fighter II Turbo HD RemixReleased: November 25, 2008Publisher: Capcom
- Sonic UnleashedReleased: November 27, 2008Developer: Sonic Team
- Destroy All Humans! Path of the FuronReleased: December 1, 2008Publisher: THQ
- 428: Shibuya ScrambleReleased: December 4, 2008Developer: Chunsoft
- Disney Sing ItReleased: December 4, 2008Developer: Zoë Mode
- Dangeresque 3: The Criminal ProjectiveReleased: December 5, 2008Developer: Telltale Games
- Dynasty Warriors: Gundam 2Released: December 18, 2008Developer: Koei
- Hiiro no KakeraReleased: December 18, 2008Developer: Otomate, Design Factory
- White Knight ChroniclesReleased: December 25, 2008Developer: Level-5
- Madden NFL ArcadeReleased: 2009Developer: EA Orlando
- 8-Bit Is EnoughReleased: January 2, 2009Developer: Telltale Games
- Grand Theft Auto IVReleased: January 4, 2009Developer: Rockstar Toronto
- The Lord of the Rings: ConquestReleased: January 9, 2009Developer: Pandemic Studios
- GTI Club+: Rally Côte d'AzurReleased: January 15, 2009Developer: Sumo Digital
- Skate 2Released: January 21, 2009Series: Skate
- Days of ThunderReleased: February 5, 2009Developer: Piranha Games
- Demon's SoulsReleased: February 5, 2009Developer: FromSoftware
- F.E.A.R. 2: Project OriginReleased: February 10, 2009Developer: Monolith Productions
- The House of the Dead: OverkillReleased: February 10, 2009Developer: Kuju Ltd.
- Shellshock 2: Blood TrailsReleased: February 13, 2009Developer: Rebellion Developments
- Disney Sing It! – High School Musical 3: Senior YearReleased: February 17, 2009Developer: Zoë Mode
- Star Ocean: The Last HopeReleased: February 19, 2009Developer: Tri-Ace
- Puzzle Quest: GalactrixReleased: February 24, 2009Developer: Infinity Plus Two
- Dynasty Warriors: StrikeforceReleased: February 26, 2009Developer: Koei Tecmo Holdings
- Killzone 2Released: February 26, 2009Developer: Sony Interactive Entertainment, Guerrilla Games
- Way of the Samurai 3Released: February 26, 2009Developer: Acquire
- Yakuza 3Released: February 26, 2009Series: Yakuza
- Watchmen: The End Is NighReleased: March 4, 2009Developer: Deadline Games
- Flight ControlReleased: March 5, 2009Developer: Firemonkeys Studios
- Resident Evil 5Released: March 5, 2009Developer: Capcom
- Musou Orochi ZReleased: March 12, 2009Developer: Koei
- Trivial PursuitReleased: March 12, 2009Developer: EA Bright Light
- Persona 4Released: March 13, 2009Series: Persona
- Trash PanicReleased: March 19, 2009Developer: Japan Studio
- SingStar QueenReleased: March 20, 2009Developer: London Studio
- The Treasures of MontezumaReleased: March 24, 2009Platforms: PlayStation 3, Microsoft Windows, Nintendo DS, PlayStation Portable, PlayStation Vita, Windows Phone, Android
- KarmaStarReleased: March 25, 2009Developer: Arkane Studios
- 007: Quantum of SolaceReleased: March 26, 2009Developer: Treyarch
- Buzz!: Brain of the WorldReleased: March 27, 2009Publisher: Sony Interactive Entertainment
- Leisure Suit Larry: Box Office BustReleased: March 27, 2009Developer: Team17
- The Chronicles of Riddick: Assault on Dark AthenaReleased: April 7, 2009Developer: Starbreeze Studios
- The Godfather IIReleased: April 7, 2009Developer: Visceral Games
- The King of Fighters XIIReleased: April 10, 2009Developer: SNK
- Terminator SalvationReleased: May 1, 2009Developer: Grin
- X-Men Origins: WolverineReleased: May 1, 2009Developer: Raven Software
- MinecraftReleased: May 17, 2009Developer: Mojang Studios, Microsoft
- Bionic CommandoReleased: May 19, 2009Developer: Grin
- Guitar Hero: MetallicaReleased: May 27, 2009Developer: Neversoft
- Dynasty Warriors 6Released: May 28, 2009Developer: Koei Tecmo Holdings
- Virtua Tennis 2009Released: May 28, 2009Developer: Sumo Digital
- InFamousReleased: May 29, 2009Series: InFamous
- Kingdom Hearts 358/2 DaysReleased: May 30, 2009Developer: Square Enix
- Red Faction: GuerrillaReleased: June 2, 2009Series: Red Faction
- The Sims 3Released: June 2, 2009Developer: The Sims Studio, Maxis, EA Mobile, Edge of Reality
- Tiger Woods PGA Tour 10Released: June 8, 2009Developer: EA Orlando
- PrototypeReleased: June 9, 2009Developer: Radical Entertainment
- Bomberman UltraReleased: June 11, 2009Developer: Hudson Soft
- Overlord IIReleased: June 23, 2009Developer: Electronic Arts, Triumph Studios
- Guitar Hero Smash HitsReleased: June 24, 2009Developer: Beenox
- Atelier Rorona: The Alchemist of ArlandReleased: June 25, 2009Developer: Gust Co. Ltd.
- Call of Juarez: Bound in BloodReleased: June 30, 2009Series: Call of Juarez
- Hatsune Miku: Project DIVAReleased: July 2, 2009Developer: Crypton Future Media
- TrineReleased: July 3, 2009Developer: Frozenbyte
- Tales of Monkey IslandReleased: July 7, 2009Developer: Telltale Games
- Battlefield 1943Released: July 8, 2009Developer: DICE
- Rock Band: Country Track PackReleased: July 21, 2009Developer: Harmonix Music Systems
- Katamari ForeverReleased: July 23, 2009Developer: Bandai Namco Holdings
- Toro to MorimoriReleased: July 23, 2009Series: Doko Demo Issyo
- Tales of Monkey Island Chapter 1: Launch of the Screaming NarwhalReleased: July 27, 2009Developer: Telltale Games
- G.I. Joe: The Rise of CobraReleased: August 4, 2009Developer: Double Helix Games
- Teenage Mutant Ninja Turtles: Turtles in Time Re-ShelledReleased: August 5, 2009Platforms: PlayStation 3