| F-1 Grand Prix | 6 | racing video game | — |
| F-1 Spirit | 3 | racing video game | — |
| F-22 | 3 | combat flight simulator game | — |
| F-Zero | 11 | science fiction video game, racing video game | — |
| F1 | 17 | racing video game | Codemasters, EA Sports |
| F1 | 3 | sim racing | EA Sports |
| Fabula Nova Crystallis Final Fantasy | 6 | role-playing video game | Square Enix |
| Falcon | 2 | combat flight simulator game | Spectrum HoloByte |
| Famicom Detective Club | 6 | adventure video game | — |
| Family Feud | 10 | game show video game | — |
| Famimaga Disk | 4 | puzzle video game | — |
| Fancy Pants Adventures | — | platform game | Armor Games |
| Fantasy Tavern Sextet | — | isekai, visual novel, harem, romance adventure game | Qureate |
| Far Cry | 20 | first-person shooter | Buka Entertainment, Softclub |
| Farm Frenzy | 4 | casual game, time management video game, agricultural science, city-building game | Alawar Entertainment |
| Farm Manager | 3 | farming simulation game | — |
| Farming Simulator | 16 | simulation video game | Focus Entertainment |
| Fatal Frame | 7 | survival horror | Wanadoo, Koei Tecmo Games, Xbox Game Studios, Nintendo, Take-Two Interactive |
| Fatal Fury | 10 | fighting game | — |
| Fate | 10 | — | — |
| Fault | 3 | visual novel | — |
| Fem myror är fler än fyra elefanter | 2 | — | Young Genius |
| Femdom Game World | 8 | erotic video game, visual novel | Femdom Game World |
| Femdom University | 2 | dating sim, erotic video game | SaliaCoel |
| Femdom Waifu | 7 | erotic video game | Zee Vital |
| FIFA Manager | 13 | association football video game, association football management game | EA Sports |
| FIFA World Cup | 13 | association football video game | — |
| Fight Night | 3 | sports video game | Electronic Arts |
| Final Fantasy | 1 | role-playing game | — |
| Final Fantasy Crystal Chronicles | 5 | action role-playing game, role-playing game, city-building game | Nintendo |
| Final Fantasy Legend | 4 | role-playing video game | Square |
| Final Fight | 6 | beat 'em up | — |
| Fire Department | 3 | real-time strategy | Gameforge |
| Fire Emblem | 23 | tactical role-playing game | Nintendo |
| Fire Pro Wrestling | 11 | professional wrestling video game | — |
| Fireboy and Watergirl | — | puzzle video game, puzzle-platformer, platform game | Armor Games |
| Firefly | 1 | space Western | — |
| Five Nights at Candy's | 3 | survival horror | — |
| Five Nights at Leon's | 5 | survival game | — |
| FlatOut | 7 | racing video game | Strategy First |
| Flight Simulator | 3 | flight simulation video game | Sublogic |
| Flight Unlimited | 3 | flight simulation video game | — |
| FLOWERS | 4 | yuri game, visual novel | — |
| Flying Shark | 2 | vertically scrolling shooter | Taito, Toaplan |
| Football Manager | 32 | association football video game, association football management game | — |
| Football Manager | 4 | association football video game, association football management game | — |
| Ford Racing | 2 | racing video game | Empire Interactive |
| Ford Simulator | 3 | racing video game | — |
| Formula One | 1 | — | — |
| Forza Motorsport | 8 | sim racing | Xbox Game Studios |
| Fragment’s Note | 7 | visual novel | — |
| Franchise Hockey Manager | 8 | sports video game | — |
| Freddi Fish | 7 | point-and-click adventure | — |
| Freespace | 2 | — | — |
| Frenetic Five | — | interactive fiction | — |
| Friday the 13th | 1 | slasher film | — |
| Fright Night | 1 | vampire film | — |
| Fritz | — | turn-based strategy video game | ChessBase |
| Front Mission | 12 | tactical role-playing game | Square |
| Front Page Sports Baseball | 3 | baseball video game | — |
| Fuckstory | — | text-based video game | — |
| Fun School | — | educational video game | — |
| Furry Legends | — | platform game | — |
| Futakoi | 1 | harem | — |