- 3-D Ultra Pinball: ThrillrideSeries: 3-D Ultra PinballReleased: 2000
- 3-D Ultra Pinball: ThrillrideSeries: 3-D Ultra PinballReleased: 2000
- 625 Sandwich StackerReleased: 2000Engine: Adobe Flash
- A2 Racer III: Europa TourDeveloper: Davilex GamesSeries: A2 Racer
- A2 Racer IV - The Cop's RevengeDeveloper: Davilex GamesSeries: A2 Racer
- AmsterdoomDeveloper: Davilex GamesReleased: 2000
- Angelique TroisDeveloper: KoeiSeries: Angelique
- Anstoss 3Developer: AscaronSeries: On the Ball
- ArcateraReleased: 2000Platforms: Microsoft Windows
- Areena 5Series: AreenaReleased: 2000
- Azure DreamsReleased: 2000Platforms: Game Boy Color
- Batman Beyond: Return of the JokerDeveloper: KemcoReleased: 2000
- Bugs Bunny in Crazy Castle 4Developer: Kotobuki SystemReleased: 2000
- Bygg båtar med Mulle MeckSeries: Gary GadgetReleased: 2000
- Bygg flygplan med Mulle MeckDeveloper: Unique Development StudiosSeries: Gary Gadget
- Combat Flight Simulator 2Developer: Xbox Game StudiosSeries: Microsoft Combat Flight Simulator
- ComunioReleased: 2000Platforms: Android
- Crack Attack!Released: 2000Platforms: Microsoft Windows, macOS, Linux
- CrocReleased: 2000Platforms: Game Boy Color
- Cultures: Discovery of VinlandSeries: CulturesReleased: 2000
- Cupid Bistro!!Released: 2000Platforms: Microsoft Windows
- Dawn of WarReleased: 2000Publisher: Virgin Interactive, SouthPeak Games
- Densha de Go! 3 Tsūkin-henDeveloper: TaitoSeries: Densha de Go!
- Destroy IReleased: 2000Genre: puzzle video game
- Deutschland Europameister 2000Developer: Davilex GamesReleased: 2000
- Disney's 102 Dalmatians: Activity CenterDeveloper: Terraglyph Interactive StudiosReleased: 2000
- DragonReleased: 2000Platforms: Nintendo Entertainment System hardware clone
- Earth 2150: The Moon ProjectDeveloper: TopWare InteractiveSeries: Earth
- Evil Islands: Curse of the Lost SoulDeveloper: NivalReleased: 2000
- Evolution: Eternal DungeonsDeveloper: StingReleased: 2000
- Family FeudDeveloper: Artech Digital EntertainmentSeries: Family Feud
- Fem myror är fler än fyra elefanter - andra delenSeries: Fem myror är fler än fyra elefanterReleased: 2000
- Final Fantasy ?Released: 2000Engine: RPG Maker 2000
- Galilei 2: Seikkailujen saariReleased: 2000Platforms: Microsoft Windows
- GeorunnerDeveloper: Ohio Distinctive SoftwareReleased: 2000
- Grachten RacerDeveloper: Davilex GamesSeries: A2 Racer
- Gungriffon BlazeDeveloper: Game ArtsSeries: Gungriffon
- Hokuto no Ken: Seiki Matsukyu Seishi DensetsuReleased: 2000Genre: action game, beat 'em up
- Holiday RacerDeveloper: Davilex GamesSeries: A2 Racer
- Hugo: The Quest for the SunstonesDeveloper: Interactive Television EntertainmentSeries: List of Hugo video games
- I Love You!Released: 2000Genre: hentai
- Invasion DeutschlandDeveloper: Davilex GamesReleased: 2000
- Jagged Alliance 2: Unfinished BusinessDeveloper: Sir-TechSeries: Jagged Alliance
- JournalistReleased: 2000Platforms: personal computer
- JumpStart Adventures 4th Grade: Sapphire FallsSeries: JumpStart franchiseReleased: 2000
- Knockout Kings 2001Series: Knockout KingsReleased: 2000
- LadangelReleased: 2000Platforms: Nintendo Entertainment System hardware clone
- Lego Alpha TeamSeries: LegoReleased: 2000
- Lego Stunt RallyReleased: 2000Platforms: Game Boy Color
- Megasoft Windel 2000Developer: CultimediaReleased: 2000
- Mia's Science Adventure: Romaine's New HatDeveloper: Kutoka InteractiveSeries: Mia's Big Adventure Collection
- Michelin Rally Masters: Race of ChampionsDeveloper: DICESeries: Test Drive
- Millennium Winter SportsDeveloper: KonamiReleased: 2000
- Monster Rancher ExplorerDeveloper: TecmoSeries: Monster Rancher, Solomon's Key
- NBA in the Zone 2000Developer: Konami Computer Entertainment OsakaSeries: NBA in the Zone
- NFL Blitz 2001Released: 2000Platforms: Game Boy Color
- NFL GameDay 2001Series: NFL GameDayReleased: 2000
- Nicktoons RacingDeveloper: Software CreationsReleased: 2000
- Pickup ExpressDeveloper: Unique Development StudiosReleased: 2000
- Pixeline for fulde sejlDeveloper: Studio 1-2Series: Pixeline
- RedCat (Demo Disc)Developer: Davilex GamesSeries: RedCat
- RedCat: Rekenen 2 - De Snelle SommenraceDeveloper: Davilex GamesSeries: RedCat
- RematchReleased: 2000Genre: one-move game
- Rhino RumbleDeveloper: TelegamesReleased: 2000
- Ronny & JuliaDeveloper: FramfabSeries: SVT's Christmas Calendar games
- Ronny & Julia i rampljusetDeveloper: FramfabReleased: 2000
- Roommania #203Released: 2000Genre: life simulation game
- Simple 1500 Jitsuyou Series Vol. 01: Norikae Annai: 2000-nenbanReleased: 2000Publisher: D3 Publisher
- Simple 1500 Jitsuyou Series Vol. 02: Katei no FuusuiReleased: 2000Publisher: D3 Publisher
- Simple 1500 Jitsuyou Series Vol. 03: Seimei HandanReleased: 2000Publisher: D3 Publisher
- Simple 1500 Jitsuyou Series Vol. 04: Ryouri: Teiban Ryouri Recipe ShuuReleased: 2000Publisher: D3 Publisher
- Ski Resort TycoonDeveloper: Cat Daddy GamesReleased: 2000
- Skippy: The Curse of the Temple of OckReleased: 2000Platforms: Microsoft Windows, macOS
- Skrotens hjältarDeveloper: Korkeken Interactive StudioReleased: 2000
- Smash Court 3Released: 2000
- Space DebrisReleased: 2000
- Space ImpactSeries: Space ImpactReleased: 2000
- Steel BeastsReleased: 2000Platforms: Microsoft Windows
- Steel Panthers: World at WarSeries: Steel PanthersReleased: 2000
- Stöck Wyys Stich PlatinumDeveloper: OptobyteReleased: 2000
- Supercross FreestyleReleased: 2000Platforms: Game Boy Color
- Tales of Lerthule IReleased: 2000Engine: RPG Maker 95
- TechnoMotionReleased: 2000Platforms: arcade video game machine
- Test Drive CyclesSeries: Test DriveReleased: 2000
- The Big Adventure of Owata's LifeReleased: 2000Engine: Adobe Flash
- The F.A. Premier League Stars 2001Developer: Electronic Arts, Krisalis SoftwareReleased: 2000
- The Last Blade: Beyond the DestinyDeveloper: SNKReleased: 2000
- The Mystery at Greveholm 3: The Old LegendDeveloper: FramfabSeries: The Mystery at Greveholm
- ThunderbirdsReleased: 2000Publisher: The Sales Curve
- Tiefer als man denkt: Jumping Jokers im PreisfallReleased: 2000Publisher: Swisscom
- Total Soccer 2000Released: 2000Platforms: Game Boy Color
- UEFA Champions League Season 1999/2000Developer: Silicon Dreams StudiosSeries: AFRICAN Champions League (ACL)
- Vietnam: Black OpsReleased: 2000Publisher: ValuSoft
- Virtual Pool 3Developer: CelerisSeries: Virtual Pool
- Virtual SkipperReleased: 2000Platforms: Microsoft Windows
- Grand Theft AutoDeveloper: Rockstar LincolnSeries: Grand Theft Auto
- Rasen KairōDeveloper: ÂgeSeries: Rasen Kairō
- Mesaze! Kanji-OuReleased: January 20, 2000Country of origin: Japan
- S&M UniversityReleased: January 20, 2000Genre: hentai, visual novel
- Umihara Kawase Shun 2nd EditionSeries: Umihara KawaseReleased: January 20, 2000
- Reel Fishing IIDeveloper: Victor Interactive SoftwareSeries: Reel Fishing
- Resident Evil SurvivorDeveloper: CapcomReleased: January 27, 2000
- Kaseki no UtaDeveloper: ÂgeReleased: January 28, 2000
- Ohanabatake no FloreDeveloper: Kogado StudioReleased: January 28, 2000
- White: Setsunasa no KakeraDeveloper: NekoNeko SoftReleased: January 28, 2000
- Brunswick Circuit Pro Bowling 2Developer: Adrenalin Entertainment, Sennari GamesReleased: January 31, 2000
- 1 On 1 GovernmentReleased: February 2000Platforms: arcade video game machine
- PBA Tour Bowling 2Developer: Bethesda SoftworksReleased: February 2000
- Resident Evil – Code: VeronicaDeveloper: CapcomReleased: February 3, 2000
- The SimsDeveloper: MaxisReleased: February 4, 2000
- Sega GTDeveloper: Sega WowReleased: February 17, 2000
- Treasure StrikeDeveloper: H.a.n.d.Released: February 17, 2000
- Romance of the Three Kingdoms VIIDeveloper: KoeiSeries: Romance of the Three Kingdoms
- Trade & Battle: Card HeroDeveloper: Nintendo Research & Development 1Released: February 21, 2000
- Cool Boarders PocketDeveloper: UEP SystemsSeries: Cool Boarders
- Fear EffectDeveloper: Kronos Digital EntertainmentReleased: February 24, 2000
- Ōgami Ichirō Funtō-ki: Sakura Taisen Kayō Shō "Kurenai Tokage" yoriReleased: February 24, 2000Genre: adventure video game
- Beatmania IIDX 3rd StyleDeveloper: KonamiSeries: Beatmania IIDX
- D+VINE[LUV]Developer: Abogado PowersReleased: February 25, 2000
- Triangle Heart: Love Love OmochabakoReleased: February 25, 2000Platforms: Microsoft Windows
- SimCity 64Developer: HAL LaboratorySeries: SimCity
- Need for Speed: Porsche UnleashedSeries: Need for SpeedReleased: February 29, 2000
- Pokemon Play it! Version 2Released: February 29, 2000Publisher: Wizards of the Coast
- Pokémon StadiumDeveloper: HAL Laboratory, Nintendo Entertainment Analysis & DevelopmentSeries: Pokémon Stadium
- Thief IIDeveloper: Looking Glass StudiosSeries: Thief
- DrummaniaReleased: March 2000Genre: music video game
- WWF SmackDown!Developer: Yuke'sSeries: WWE 2K
- Kakinoki Shogi IVDeveloper: Yoshikazu KakinokiReleased: March 4, 2000
- Ridge Racer VDeveloper: NamcoReleased: March 4, 2000
- Might and Magic VIII: Day of the DestroyerDeveloper: New World ComputingReleased: March 7, 2000
- Army Men: Air TacticsDeveloper: The 3DO CompanySeries: Army Men
- Rollcage Stage IIDeveloper: Attention to DetailReleased: March 8, 2000
- Aitakute...Your Smiles in My HeartReleased: March 16, 2000Genre: dating sim
- Top Gear Hyper BikeDeveloper: Snowblind StudiosSeries: Top Gear
- Wario Land 3Developer: Nintendo Research & Development 1Released: March 21, 2000
- Metal Slug 3Developer: SNKSeries: Metal Slug
- Seireiki RaybladeDeveloper: WinkysoftReleased: March 23, 2000
- Kirby 64: The Crystal ShardsDeveloper: HAL LaboratoryReleased: March 24, 2000
- School DaysReleased: March 24, 2000Platforms: Microsoft Windows, DVD Player
- Soldier of FortuneDeveloper: Raven SoftwareSeries: Soldier of Fortune
- Final Fight RevengeDeveloper: CapcomSeries: Final Fight
- Marvel vs. Capcom 2: New Age of HeroesDeveloper: CapcomReleased: March 30, 2000
- MDK 2Developer: BiowareReleased: March 31, 2000
- Microsoft Baseball 2001Developer: Xbox Game StudiosSeries: Microsoft Baseball
- Premier Manager 2000Series: Premier ManagerReleased: March 31, 2000
- Romance of the Three Kingdoms VI: Awakening of the DragonDeveloper: KoeiSeries: Romance of the Three Kingdoms
- Crosscountry Canada PlatinumSeries: CrosscountryReleased: April 2000
- Skipper & Skeeto: Take a BreakDeveloper: Ivanoff InteractiveReleased: April 2000
- Haruka: Beyond the Stream of TimeDeveloper: Ruby PartyReleased: April 6, 2000
- Gaia MasterDeveloper: CapcomReleased: April 13, 2000
- Gradius III and IVDeveloper: KonamiReleased: April 13, 2000
- Mega Man Legends 2Developer: CapcomSeries: Mega Man Legends
- Castle Fantasia Erencia SenkiDeveloper: Studio e.go!Released: April 21, 2000
- Fukakutei Sekai no Tantei ShinshiReleased: April 21, 2000Platforms: Microsoft Windows
- Heartful Memories: Little Witch Parfait 2Released: April 21, 2000Publisher: Kogado Studio
- MediEvil 2Developer: Guerrilla CambridgeSeries: MediEvil
- Midtown Madness 2Series: Midtown MadnessReleased: April 22, 2000
- Breath of Fire IVDeveloper: CapcomReleased: April 27, 2000
- Metal Gear SolidDeveloper: Tose Co.Series: Metal Gear
- The Legend of Zelda: Majora's MaskDeveloper: Nintendo Entertainment Analysis & DevelopmentSeries: The Legend of Zelda
- AriesDeveloper: CircusReleased: April 28, 2000
- Dino Breeder 4Released: April 28, 2000Platforms: Game Boy Color
- UEFA Euro 2000Developer: Electronic ArtsSeries: UEFA Euro
- Nightmare Creatures IIDeveloper: Kalisto EntertainmentSeries: Nightmare Creatures
- Excitebike 64Released: April 30, 2000Publisher: Nintendo
- Colony Wars: Red SunDeveloper: SCE Studio LiverpoolReleased: May 2, 2000
- 4 Wheel ThunderDeveloper: Kalisto EntertainmentReleased: May 4, 2000
- Mr. DrillerDeveloper: NamcoReleased: May 10, 2000
- Driver: You Are the WheelmanReleased: May 16, 2000Platforms: Game Boy Color
- Brigandine: Grand EditionReleased: May 18, 2000Platforms: PlayStation 3, PlayStation Portable, PlayStation Vita
- Cosmowarrior ZeroDeveloper: TaitoReleased: May 18, 2000
- GekidoReleased: May 18, 2000Publisher: Interplay Entertainment
- Runabout 2Series: RunaboutReleased: May 19, 2000
- Earth 2150Developer: TopWare InteractiveSeries: Earth
- Metal Slug 2nd MissionSeries: Metal SlugReleased: May 22, 2000
- Perfect DarkDeveloper: Rare Ltd.Series: Perfect Dark
- Field & Stream: Trophy Bass 4Released: May 25, 2000Platforms: Microsoft Windows
- Motocross Madness 2Developer: THQSeries: Motocross Madness
- Natural2 -Duo-Developer: FairytaleReleased: May 26, 2000
- Mary-Kate and Ashley: Get A ClueReleased: May 31, 2000Platforms: Game Boy Color
- Combat Mission: Beyond OverlordDeveloper: Battlefront.comSeries: Combat Mission
- Spec Ops: Stealth PatrolSeries: Spec OpsReleased: June 5, 2000
- ISS Pro EvolutionDeveloper: KonamiReleased: June 6, 2000
- Tomb RaiderDeveloper: Core DesignSeries: Tomb Raider
- Shogun: Total WarDeveloper: Creative AssemblySeries: Total War
- Beach Head 2000Released: June 15, 2000Publisher: WizardWorks Software
- Tomba! 2: The Evil Swine ReturnDeveloper: Whoopee CampReleased: June 16, 2000
- 1944: The Loop MasterDeveloper: EightingSeries: 19XX
- Heroes of Might and MagicSeries: Heroes of Might and MagicReleased: June 20, 2000
- Iron Soldier 3Developer: Eclipse Software DesignReleased: June 20, 2000
- Star Trek: Klingon AcademyDeveloper: Interplay EntertainmentReleased: June 21, 2000
- Boku no NatsuyasumiDeveloper: Millennium KitchenSeries: Boku no Natsuyasumi
- Legend of Ogre Battle Gaiden: Prince of ZenobiaDeveloper: QuestReleased: June 22, 2000
- Tokyo Xtreme Racer 2Developer: GenkiSeries: Tokyo Xtreme Racer
- Truck KyōsōkyokuDeveloper: Metro CorporationReleased: June 22, 2000
- Deus ExDeveloper: Ion StormReleased: June 23, 2000
- Eve ZeroReleased: June 23, 2000Publisher: Suntendy Interactive Multimedia Co.,Ltd.
- Icewind DaleDeveloper: Black Isle StudiosSeries: Icewind Dale
- Persona 2: Eternal PunishmentSeries: PersonaReleased: June 29, 2000
- Pocket Digimon WorldDeveloper: BandaiReleased: June 29, 2000
- Destruction Derby RawDeveloper: Studio 33Series: Destruction Derby
- Hateshinaku Aoi, Kono Sora no Shita de...Developer: TopcatReleased: June 30, 2000
- Mortal Kombat: Special ForcesDeveloper: Midway GamesSeries: Mortal Kombat
- Wacky RacesReleased: June 30, 2000Platforms: Game Boy Color
- Star WraithSeries: Star WraithReleased: July 2000
- Lagnacure LegendReleased: July 6, 2000Country of origin: Japan
- Suzuki BakuhatsuReleased: July 6, 2000Genre: puzzle video game
- Warlords BattlecrySeries: Warlords BattlecryReleased: July 9, 2000
- Blaster Master: Blasting AgainDeveloper: SunsoftReleased: July 13, 2000
- Inagawa Junji: Mayonaka no TaxiReleased: July 13, 2000Genre: visual novel
- Dokapon MillenniumQuestDeveloper: Asmik Ace EntertainmentSeries: Dokapon
- World Series Baseball 2K1Developer: Sega WowSeries: World Series Baseball
- One Piece: Become the Pirate King!Developer: BandaiReleased: July 19, 2000
- Syphon Filter 2Developer: Bend StudioSeries: Syphon Filter
- Mario TennisDeveloper: Camelot Software PlanningSeries: Mario Tennis
- NCAA Football 2001Series: EA Sports College FootballReleased: July 26, 2000
- The King of Fighters 2000Developer: SNKSeries: The King of Fighters, The King of Fighters
- Bikkuri MouseDeveloper: Sony Interactive EntertainmentReleased: July 27, 2000
- Digimon World 2Developer: BandaiReleased: July 27, 2000
- Turok 3: Shadow of OblivionDeveloper: Bit ManagersSeries: Turok
- Twilight Syndrome: SaikaiSeries: Twilight SyndromeReleased: July 27, 2000
- Rhapsody: A Musical AdventureDeveloper: Nippon Ichi SoftwareReleased: July 30, 2000
- Hot Chix 'n' Gear StixDeveloper: Driver-Inter, Ltd., Fiendish GamesReleased: August 2000
- Armored Core 2Developer: FromSoftwareSeries: Armored Core
- Digimon Adventure 02: Tag TamersDeveloper: BandaiReleased: August 3, 2000
- Dynasty Warriors 2Developer: Omega ForceSeries: Dynasty Warriors
- Grandia IIDeveloper: Game ArtsSeries: Grandia
- Dungeon SaviorReleased: August 4, 2000Publisher: J-Wing
- Heavy Metal: F.A.K.K. 2Developer: Ritual EntertainmentReleased: August 4, 2000
- Zok Zok HeroesDeveloper: KAZeReleased: August 4, 2000
- Urban TerrorReleased: August 5, 2000Engine: ioquake3
- Tenchu 2: Birth of the Stealth AssassinsDeveloper: AcquireSeries: Tenchu
- Eternal Fighter ZeroDeveloper: Twilight FrontierReleased: August 11, 2000
- Sense Off ~A Sacred Story in the Wind~Released: August 18, 2000Platforms: Microsoft Windows
- NCAA GameBreaker 2001Released: August 21, 2000Genre: American football video game
- Madden NFL 2001Developer: EA OrlandoSeries: Madden NFL
- ATV Quad Power RacingReleased: August 23, 2000Genre: racing video game
- Kirby Tilt 'n' TumbleDeveloper: HAL LaboratoryReleased: August 23, 2000
- Dance Dance Revolution 4thMixDeveloper: KonamiSeries: Dance Dance Revolution
- Grand Prix 3Developer: MicroProseSeries: Grand Prix
- Pure MailReleased: August 25, 2000Platforms: Microsoft Windows
- Sensei 2Released: August 25, 2000Publisher: G-Collections
- Water Closet: The Forbidden ChamberReleased: August 25, 2000Publisher: Peach Princess
- Dragon Quest VIIDeveloper: HeartbeatSeries: Dragon Quest
- Perfect DarkDeveloper: Rare Ltd.Series: Perfect Dark
- Gin'iroReleased: August 31, 2000Platforms: Microsoft Windows
- Ganbare unten-shi!!Series: Densha de Go!Released: September 2000
- Gobs of GamesDeveloper: 2n ProductionsReleased: September 2000
- Carmageddon TDR 2000Developer: Torus GamesSeries: Carmageddon
- Mysterious SongReleased: September 3, 2000Platforms: TurboGrafx-16
- Maximum PoolReleased: September 8, 2000Platforms: Microsoft Windows
- Dino Crisis 2Developer: CapcomSeries: Dino Crisis
- Lego Stunt RallyDeveloper: Graphic State GamesSeries: Lego
- Oha Suta Dance Dance RevolutionDeveloper: KonamiSeries: Dance Dance Revolution
- Crimson SkiesDeveloper: Zipper InteractiveReleased: September 17, 2000
- Duke Nukem: Land of the BabesDeveloper: N-SpaceReleased: September 19, 2000
- Tony Hawk's Pro Skater 2Developer: NeversoftReleased: September 20, 2000
- Pokémon Puzzle ChallengeDeveloper: Intelligent SystemsSeries: Puzzle League
- Baldur's Gate II: Shadows of AmnDeveloper: BiowareReleased: September 22, 2000
- Eye's Only: Sono Kagayaki wa Mabushisa ni MichiteReleased: September 22, 2000Platforms: Microsoft Windows
- Frogger 2: Swampy's RevengeDeveloper: Blitz GamesReleased: September 23, 2000
- Galaga: Destination EarthSeries: GalaxianReleased: September 23, 2000
- Spin JamReleased: September 24, 2000Publisher: Empire Interactive
- Pokémon Puzzle LeagueDeveloper: Nintendo Software TechnologySeries: Puzzle League
- Dave Mirra Freestyle BMXDeveloper: Underground DevelopmentReleased: September 26, 2000
- NHL 2001Developer: EA VancouverReleased: September 26, 2000
- BealpharethReleased: September 28, 2000Genre: action role-playing game
- Beatmania GB GatchaMIX2Series: BeatmaniaReleased: September 28, 2000
- Beatmania IIDX 4th StyleDeveloper: KonamiSeries: Beatmania IIDX
- Gunparade MarchReleased: September 28, 2000Genre: mecha video game, tactical role-playing game
- Elevator Action EXDeveloper: AltronReleased: September 29, 2000
- Moto Racer World TourDeveloper: Delphine Software InternationalReleased: September 29, 2000
- RollerCoaster Tycoon: Loopy LandscapesSeries: RollerCoaster TycoonReleased: September 30, 2000
- Crackin' DJReleased: October 2000Platforms: Sega NAOMI, arcade video game machine
- Dance Dance Revolution USADeveloper: KonamiSeries: Dance Dance Revolution
- Ski Jump International 3Series: Ski Jump InternationalReleased: October 1, 2000
- Blair Witch Volume I: Rustin ParrSeries: Blair Witch VolumesReleased: October 3, 2000
- Micro ManiacsDeveloper: CodemastersSeries: Micro Machines
- Formula One 2000Developer: Studio 33Released: October 6, 2000
- Spyro: Year of the DragonDeveloper: Insomniac GamesReleased: October 11, 2000
- Mario Party 2Developer: Hudson SoftSeries: Mario Party
- Cruis'n ExoticaDeveloper: Midway GamesSeries: Cruis'n
- NBA Live 2001Developer: EA SportsSeries: NBA Live
- SWAT 3: Close Quarters Battle: Elite EditionSeries: SWATReleased: October 18, 2000
- Mega Man XtremeDeveloper: CapcomSeries: Mega Man X
- Command & Conquer: Red Alert 2Developer: Westwood StudiosReleased: October 23, 2000
- Medal of Honor: UndergroundDeveloper: Dreamworks InteractiveSeries: Medal of Honor
- Cool Boarders 2001Series: Cool BoardersReleased: October 24, 2000
- Fushigi DekaReleased: October 26, 2000Publisher: Capcom
- Midnight Club: Street RacingSeries: Midnight ClubReleased: October 26, 2000
- SSXDeveloper: EA VancouverSeries: SSX
- TimeSplittersDeveloper: Crytek UKSeries: TimeSplitters
- Baldr BulletReleased: October 27, 2000Platforms: Microsoft Windows
- Championship Manager: Season 00/01Developer: Sports InteractiveSeries: Championship Manager
- Sudden StrikeReleased: October 27, 2000Publisher: Cdv Software Entertainment
- FIFA 2001Developer: EA VancouverReleased: October 30, 2000
- Batta Batta: Kampen mod UltraDeveloper: Studio 1-2Released: November 2000
- Elves in Paradise: Elf Bowling 2Developer: NStormReleased: November 2000
- Karpov Schach 2000Developer: Cdv Software EntertainmentReleased: November 2000
- Lunatic Dawn: 3rd BookSeries: Lunatic DawnReleased: November 2000