- 1941: Counter AttackDeveloper: CapcomSeries: 19XX
- 4D Sports TennisDeveloper: Distinctive SoftwareReleased: 1990
- Adult TwoReleased: 1990Platforms: Amstrad CPC
- African Trail SimulatorReleased: 1990Platforms: DOS, ZX Spectrum, Amstrad CPC, MSX
- AntaresDeveloper: Nightmare ProductionsReleased: 1990
- Baseball Stars ProfessionalDeveloper: SNKReleased: 1990
- Batman: The Video GameReleased: 1990Platforms: Game Boy
- Battle RoyaleDeveloper: Incredible TechnologiesReleased: 1990
- Benthal WorldDeveloper: Thin Chen EnterpriseReleased: 1990
- BoxyboyReleased: 1990Publisher: NEC
- BreakdownReleased: 1990Platforms: Amstrad CPC
- BSS Jane SeymourReleased: 1990Publisher: Gremlin Interactive, Konami
- Buck Rogers: Countdown to DoomsdayDeveloper: Strategic SimulationsSeries: Gold Box
- Burai: Hachigyoku no yūshi densetsuReleased: 1990Genre: role-playing video game
- CadaverDeveloper: The Bitmap BrothersReleased: 1990
- Champions of KrynnDeveloper: Strategic SimulationsSeries: Gold Box
- Chess Champion 2175Released: 1990Platforms: DOS, Atari ST, Mac
- Chess SimulatorDeveloper: Oxford SoftworksReleased: 1990
- Colossus Chess XSeries: Colossus ChessReleased: 1990
- Columns IISeries: ColumnsReleased: 1990
- Colwyns AbenteuerReleased: 1990Publisher: LOGO Software
- Conflict: Middle East Political SimulatorReleased: 1990Publisher: Virgin Interactive
- Crazy SueReleased: 1990Platforms: Commodore 64
- CreaturesDeveloper: Apex Computer ProductionsReleased: 1990
- Das StundenglasDeveloper: WeltenschmiedeReleased: 1990
- Decision at GettysburgReleased: 1990Platforms: DOS
- Deep Dungeon IV: Kuro no YōjutsushiDeveloper: Hummingbird SoftSeries: Deep Dungeon
- Design Your Own RailroadReleased: 1990Platforms: Classic Mac OS, DOS
- DinosaurReleased: 1990Platforms: NEC PC-8800 series, Microsoft Windows, NEC PC-9800 series, FM Towns
- Dottori KunReleased: 1990Genre: arcade
- DragonflightDeveloper: Thalion SoftwareReleased: 1990
- Driver's EyesDeveloper: NamcoReleased: 1990
- Edward O. Thorp's Real BlackjackReleased: 1990Platforms: DOS
- Emerald Mine 3 ProfessionalSeries: Emerald MineReleased: 1990
- Escape from HellDeveloper: Electronic ArtsReleased: 1990
- Evil StoneReleased: 1990Platforms: arcade video game machine
- Explora IIIDeveloper: InfomediaReleased: 1990
- Eye of the BeholderDeveloper: Strategic Simulations, Westwood StudiosReleased: 1990
- Fatal HeritageDeveloper: EgosoftReleased: 1990
- Fountain of DreamsDeveloper: Electronic ArtsSeries: Wasteland
- Fray in Magical AdventureDeveloper: MicrocabinReleased: 1990
- Fun with BlupiDeveloper: Epsitec SAReleased: 1990
- Galleons of Glory: The Secret Voyage of MagellanDeveloper: BroderbundReleased: 1990
- Gauntlet: The Third EncounterDeveloper: AtariReleased: 1990
- Gazza IIDeveloper: Empire InteractiveSeries: Gazza
- Greg Norman's Shark Attack!: The Ultimate Golf SimulatorReleased: 1990Platforms: DOS, Atari ST, Commodore 64
- Gremlins 2: The New BatchSeries: GremlinsReleased: 1990
- Gremlins 2: The New BatchDeveloper: SunsoftSeries: Gremlins
- Hard NovaReleased: 1990Publisher: Electronic Arts
- HoverforceDeveloper: AccoladeReleased: 1990
- Hugo's House of HorrorsReleased: 1990Platforms: DOS
- James Pond: Underwater AgentReleased: 1990Publisher: Electronic Arts
- Jeu de DamesDeveloper: Epsitec SAReleased: 1990
- Kawa no Nushi TsuriDeveloper: Yuu YuuReleased: 1990
- Kick Off 2Series: Kick OffReleased: 1990
- Leavin' TeramisDeveloper: Thalion SoftwareReleased: 1990
- Les Manley in: Search for the KingDeveloper: AccoladeReleased: 1990
- Life & Death II: The BrainDeveloper: The Software ToolworksReleased: 1990
- Lightning FightersDeveloper: KonamiReleased: 1990
- Links: The Challenge of GolfSeries: LinksReleased: 1990
- LogoReleased: 1990Publisher: Starbyte
- Lotus Esprit Turbo ChallengeSeries: LotusReleased: 1990
- Luigi's Hammer TossReleased: 1990Publisher: Nintendo
- Magic LinesReleased: 1990Publisher: Thalion Software
- Magicland DizzyDeveloper: Big Red SoftwareSeries: Dizzy
- Mega ManReleased: 1990Platforms: DOS
- Mercenary ForceReleased: 1990Platforms: Game Boy
- MicroLeague Football: The Coach's ChallengeReleased: 1990Platforms: DOS
- Military Multipurpose Arcade Combat SimulatorReleased: 1990Platforms: Super Nintendo Entertainment System
- Murder!Released: 1990Publisher: U.S. Gold
- Murders in SpaceReleased: 1990Publisher: Ziggurat Interactive
- PGA Tour GolfDeveloper: BlueSky SoftwareSeries: PGA Tour
- Phantasy Star II Text AdventuresSeries: Phantasy StarReleased: 1990
- Quest for Glory II: Trial by FireSeries: Quest for GloryReleased: 1990
- Railroad TycoonDeveloper: MicroProseReleased: 1990
- Rat RaceDeveloper: SilverbyteReleased: 1990
- Sands of FireDeveloper: Three-Sixty PacificReleased: 1990
- SentinelDeveloper: ImagineeringReleased: 1990
- Silent Service IIDeveloper: MicroProseReleased: 1990
- Skate or Die!Developer: Electronic ArtsReleased: 1990
- SorcerianDeveloper: Aeria, G-ModeSeries: Dragon Slayer
- Spellcasting 101: Sorcerers Get All The GirlsDeveloper: Legend EntertainmentReleased: 1990
- Strider IIDeveloper: Tiertex Design StudiosSeries: Strider
- Super Mario Bros. 3Released: 1990Platforms: Nelsonic Game Watch
- Teenage Mutant Hero Turtles in Turtle ChallengeReleased: 1990Publisher: Bandai
- Teenage Mutant Ninja Turtles: World TourReleased: 1990Platforms: Atari ST, Commodore 64
- Test Drive III: The PassionDeveloper: AccoladeSeries: Test Drive
- The Bugs Bunny Birthday BlowoutDeveloper: KemcoReleased: 1990
- The Cyber ShinobiReleased: 1990Genre: action game
- The Final BattleReleased: 1990Publisher: Mirrorsoft, Personal Software Services
- The TerminatorDeveloper: Bethesda SoftworksReleased: 1990
- Tie BreakReleased: 1990Publisher: Ocean Software
- Tom and the GhostReleased: 1990Platforms: DOS, Atari ST
- Tower FraReleased: 1990Publisher: Thalion Software
- TurricanDeveloper: Rainbow Arts, Factor 5Series: Turrican
- WarlordsSeries: WarlordsReleased: 1990
- WolfpackReleased: 1990Publisher: Broderbund
- World Cup Italia '90Series: FIFA World CupReleased: 1990
- Xak II: Rising of the RedmoonDeveloper: MicrocabinReleased: 1990
- ZiriaxDeveloper: The Whiz KidzReleased: 1990
- Zock OutReleased: 1990Country of origin: Germany
- A Boy and His Blob: Trouble on BloboloniaDeveloper: ImagineeringReleased: January 1990
- AliensDeveloper: KonamiSeries: Alien
- Wizards & Warriors X: The Fortress of FearDeveloper: Rare Ltd.Released: January 1990
- Heiankyo AlienReleased: January 14, 1990Publisher: Meldac
- Wizards & WarriorsDeveloper: Rare Ltd.Released: January 17, 1990
- MercsDeveloper: CapcomSeries: Commando
- WCW WrestlingDeveloper: NichibutsuReleased: February 1990
- NemesisDeveloper: KonamiReleased: February 23, 1990
- Wheel of Fortune: Family EditionDeveloper: Rare Ltd.Series: Wheel of Fortune
- Chip 'n Dale Rescue Rangers: The Adventures in Nimnul's CastleReleased: March 1, 1990Publisher: Disney Interactive Studios
- Space Invaders: Fukkatsu no HiDeveloper: TaitoReleased: March 3, 1990
- Wizardry II: The Knight of DiamondsDeveloper: Sir-TechSeries: Wizardry
- Assault Suit LeynosDeveloper: Masaya, Nippon Computer SystemsSeries: Assault Suit
- Block HoleDeveloper: KonamiReleased: March 16, 1990
- Ikari III: The RescueDeveloper: SNK, SNKReleased: March 16, 1990
- Sansara NagaReleased: March 23, 1990Publisher: Victor Interactive Software
- King of CasinoReleased: March 27, 1990Platforms: TurboGrafx-16
- Super Dodge BallDeveloper: Technōs JapanReleased: March 30, 1990
- RayxanberDeveloper: DATA WESTSeries: Rayxanber
- Snake's RevengeDeveloper: KonamiSeries: Metal Gear
- Galaxian3: Project DragoonDeveloper: NamcoSeries: Galaxian
- Misty BlueDeveloper: EnixReleased: April 2, 1990
- Digital Devil Story: Megami Tensei IISeries: Megami TenseiReleased: April 6, 1990
- Ninja Gaiden II: The Dark Sword of ChaosDeveloper: TecmoSeries: Ninja Gaiden
- SD Rupan Sansei - Kinko yaburi daisakusenReleased: April 13, 1990Publisher: Banpresto
- SD Battle Oozumou: Heisei Hero BashoDeveloper: BanprestoSeries: Compati Hero Series
- Phantasy Star IIISeries: Phantasy StarReleased: April 21, 1990
- Parodius! From Myth to LaughterDeveloper: KonamiReleased: April 25, 1990
- NAM-1975Developer: SNKReleased: April 26, 1990
- Final Fantasy IIIDeveloper: SquareReleased: April 27, 1990
- DamoclesReleased: May 1990Genre: science fiction video game
- Rance II: Hangyaku no ShoujotachiDeveloper: AliceSoftSeries: Rance
- BoxingDeveloper: Tose Co.Released: May 18, 1990
- Nintendo World CupDeveloper: Technōs JapanReleased: May 18, 1990
- Secret of the Silver BladesDeveloper: Strategic SimulationsSeries: Gold Box, Pool of Radiance
- Double Dragon 3: The Rosetta StoneDeveloper: East Technology Corp.Series: Double Dragon
- Chip 'n Dale Rescue RangersDeveloper: CapcomReleased: June 1990
- Dragon Spirit: The New LegendDeveloper: NamcoReleased: June 1990
- Thunder Force IIIDeveloper: TechnosoftSeries: Thunder Force
- ColumnsSeries: ColumnsReleased: June 29, 1990
- GhostbustersReleased: June 29, 1990Genre: shoot 'em up, action game
- Gargoyle's QuestDeveloper: CapcomSeries: Ghosts 'n Goblins
- Star ControlDeveloper: Toys for BobReleased: July 1990
- The Adventures of Gilligan's IslandDeveloper: Human EntertainmentReleased: July 1990
- Ranma ½Developer: BanprestoReleased: July 2, 1990
- Super Star SoldierDeveloper: KanekoSeries: Star Soldier
- Captain Tsubasa Vol. II: Super StrikerDeveloper: TecmoReleased: July 20, 1990
- Devil's CrushDeveloper: Kaga CreateSeries: Crush Pinball
- Bases Loaded 3Developer: Tose Co.Released: July 27, 1990
- Spy vs. SpyDeveloper: Aackosoft, First Star SoftwareReleased: July 27, 1990
- Might and Magic Book One: The Secret of the Inner SanctumDeveloper: New World ComputingReleased: July 31, 1990
- Teenage Mutant Ninja Turtles: Fall of the Foot ClanDeveloper: KonamiReleased: August 3, 1990
- Street Fighter 2010: The Final FightDeveloper: CapcomReleased: August 8, 1990
- D: Ōshū ShinkirōDeveloper: Wolf TeamReleased: August 10, 1990
- Teenage Mutant Ninja TurtlesDeveloper: KonamiReleased: August 17, 1990
- Atomic PunkDeveloper: Hudson SoftReleased: August 31, 1990
- Dungeon KidDeveloper: QuestReleased: August 31, 1990
- BattletankDeveloper: ImagineeringReleased: September 1990
- Skate or Die 2: The Search for Double TroubleDeveloper: Electronic ArtsReleased: September 1990
- Valis IIIDeveloper: Telenet JapanSeries: Valis
- Mitsubachi GakuenDeveloper: Hudson SoftReleased: September 14, 1990
- Mega Man 3Developer: CapcomSeries: Mega Man, Mega Man Legacy Collection
- Fire Hawk: Thexder - The Second ContactDeveloper: Game ArtsReleased: October 1990
- RyukyuDeveloper: Success, ASCII CorporationSeries: Ryukyu
- StuntsDeveloper: Distinctive SoftwareReleased: October 1990
- The Secret of Monkey IslandDeveloper: Lucasfilm GamesSeries: Monkey Island
- Kwik SnaxDeveloper: Oliver TwinsSeries: Dizzy
- Super Space Invaders '91Developer: TaitoSeries: Space Invaders
- Wayne Gretzky Hockey 2Developer: Bethesda SoftworksReleased: November 1990
- Romance of the Three Kingdoms IIDeveloper: KoeiSeries: Romance of the Three Kingdoms
- King's Quest VSeries: King's QuestReleased: November 9, 1990
- The Rescue of Princess BlobetteDeveloper: ImagineeringReleased: November 9, 1990
- Parasol Henbē: Niji no DaibōkenReleased: November 16, 1990Publisher: Epoch Co.
- Castle of Illusion Starring Mickey MouseSeries: IllusionReleased: November 20, 1990
- Silent ServiceDeveloper: MicroProseReleased: November 23, 1990
- John Madden FootballDeveloper: Park Place ProductionsSeries: Madden NFL
- Power RacerReleased: December 1990Platforms: Game Boy
- Shadow Dancer: The Secret of ShinobiReleased: December 1990Platforms: Microsoft Windows, macOS, Linux
- Teenage Mutant Ninja Turtles II: The Arcade GameDeveloper: KonamiReleased: December 1990
- BombermanDeveloper: Hudson SoftReleased: December 7, 1990
- Painter MomopiiReleased: December 7, 1990Platforms: Game Boy
- Ranma 1/2Released: December 7, 1990
- Ranma ½Developer: MasayaReleased: December 7, 1990
- Commander Keen in Invasion of the VorticonsSeries: Commander KeenReleased: December 14, 1990
- Final Fantasy Legend IIDeveloper: SquareSeries: SaGa, Final Fantasy Legend
- The Krion ConquestDeveloper: Tokai CommunicationsReleased: December 14, 1990
- Tōshin ToshiDeveloper: AliceSoftSeries: Tōshin Toshi
- GodzillaSeries: GodzillaReleased: December 18, 1990
- Dragon Knight IIDeveloper: ELF CorporationSeries: Dragon Knight
- Daikaijyu DeburasuReleased: December 21, 1990Country of origin: Japan
- MUSHASeries: Power StrikeReleased: December 21, 1990
- PilotwingsDeveloper: Nintendo Entertainment Analysis & DevelopmentReleased: December 21, 1990
- Zoids mokushirokuReleased: December 21, 1990Publisher: Tomy
- StarTropicsDeveloper: Nintendo Integrated Research & DevelopmentReleased: December 26, 1990